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化驗
≥95%
形狀
powder
溶解度
0.1 M NaOH: 10 mg/mL, clear, colorless
儲存溫度
−20°C
SMILES 字串
NCCN(CCN)\[N+]([O-])=N/O
InChI
1S/C4H13N5O2/c5-1-3-8(4-2-6)9(11)7-10/h10H,1-6H2/b9-7+
InChI 密鑰
YNRCBOXEDICOIX-VQHVLOKHSA-N
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應用
3,3-双(氨基乙基)-1-羟基-2-氧代-1-三氮烯已被用作神经元培养的一氧化氮供体补充剂。它也已用作一氧化氮供体,以研究亚硝酸盐处理后蛋白S-亚硝化(SNO)的作用。
已使用3,3-双(氨基乙基)-1-羟基-2-氧代-1-三氮烯深入了解可能有助于尼可地尔在心血管系统中产生有益作用的分子途径。 3,3-双(氨基乙基)-1-羟基-2-氧代-1-三氮烯以速率控制的方式自发释放一氧化氮。
生化/生理作用
3,3-双(氨基乙基)-1-羟基-2-氧代-1-三氮烯是长效一氧化氮供体。它可能在大鼠中表现出伤害性作用。
訊號詞
Danger
危險聲明
危險分類
Self-react. C
儲存類別代碼
5.2 - Organic peroxides and self-reacting hazardous materials
水污染物質分類(WGK)
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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The ability of Mycobacterium tuberculosis (Mtb) to thrive in its phagosomal niche is critical for its establishment of a chronic infection. This requires that Mtb senses and responds to intraphagosomal signals such as pH. We hypothesized that Mtb would respond
Iris C Vermeulen Windsant et al.
Critical care (London, England), 16(3), R95-R95 (2012-05-26)
The increasing number of reports on the relation between transfusion of stored red blood cells (RBCs) and adverse patient outcome has sparked an intense debate on the benefits and risks of blood transfusions. Meanwhile, the pathophysiological mechanisms underlying this postulated
Natalia Rios et al.
Free radical biology & medicine, 101, 284-295 (2016-09-20)
The specific and sensitive detection of peroxynitrite (ONOO-/ONOOH) in biological systems is a great challenge due to its high reactivity towards several biomolecules. Herein, we validated the advantages of using fluorescein-boronate (Fl-B) as a highly sensitive fluorescent probe for the
Keigo Ueno et al.
PloS one, 6(9), e24759-e24759 (2011-09-21)
The intestinal resident Candida glabrata opportunistically infects humans. However few genetic factors for adaptation in the intestine are identified in this fungus. Here we describe the C. glabrata CYB2 gene encoding lactate dehydrogenase as an adaptation factor for survival in
A new nitric oxide donor, NOC-18, exhibits a nociceptive effect in the rat formalin model
Shibuta S, et al.
Journal of the Neurological Sciences, 141(1), 1-5 (1996)
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