所有图片(1)
About This Item
经验公式(希尔记法):
C15H15NO3 · HCl
CAS号:
分子量:
293.75
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
推荐产品
形狀
powder
品質等級
溶解度
H2O: 1 mg/mL
DMSO: 2 mg/mL
儲存溫度
2-8°C
SMILES 字串
CC1=CC(=O)Oc2c(C)c3oc(C)c(CN)c3cc12
InChI
1S/C15H15NO3/c1-7-4-13(17)19-14-8(2)15-11(5-10(7)14)12(6-16)9(3)18-15/h4-5H,6,16H2,1-3H3
InChI 密鑰
WBIICVGYYRRURR-UHFFFAOYSA-N
應用
4'-盐酸氨甲基三氧沙林可灭活 DNA 和 RNA 病毒,包括 HIV-1。4'-盐酸氨甲基三氧沙林在紫外光照射下可与核酸共价结合。
生化/生理作用
4'-盐酸氨甲基三氧沙林用于通过核酸交联和紫外线照射灭活 DNA 和 RNA 病毒,包括 HIV-1。
特點和優勢
这种化合物是细胞凋亡研究的特色产品。 点击此处 ,发现更多特色细胞凋亡产品。访问sigma.com/discover-bsm了解更多关于其他研究领域的生物活性小分子的信息。
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Carc. 2 - Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
其他客户在看
M A Reynolds et al.
Bioconjugate chemistry, 3(5), 366-374 (1992-09-11)
A method is reported for conjugating an analog of 4'-(aminomethyl)-4,5',8- trimethylpsoralen to methylphophonate oligonucleotides. This method enables the psoralen moiety to be coupled to the phosphonate backbone between any two desired bases in a sequence. When hybridized to a target
A A Oroskar et al.
Free radical biology & medicine, 20(5), 751-756 (1996-01-01)
The ability of scavengers of hydroxyl radical (OH radical) to modulate the photosensitized relaxation (induction of the first single-strand break) of supercoiled plasmid DNA with UVA photoactivated 4'-aminomethyl-4,5',8-trimethylpsoralen was examined by comparing the dose reduction factor (DRF: the ratio of
Ryan C Maves et al.
Vaccine, 29(15), 2691-2696 (2011-02-10)
Psoralens are photoreactive compounds that cross-link pyrimidines after exposure to UVA radiation. In this experiment, we tested the protective efficacy of a psoralen-inactivated dengue vaccine candidate in non-human primates. Two groups of 7 Aotus nancymaae monkeys received either 10ng per
S J Wagner et al.
Photochemistry and photobiology, 57(5), 819-824 (1993-05-01)
Psoralens and UVA light have been used in the laboratory to study the inactivation of viruses that may be infrequently present in platelet concentrates that are prepared for transfusion. In order to evaluate safety aspects of the treatment of platelet
M Beltrame et al.
The EMBO journal, 11(4), 1531-1542 (1992-04-01)
It has long been known that U3 can be isolated hydrogen bonded to pre-ribosomal RNAs, but the sites of interaction are poorly characterized. Here we show that yeast U3 can be cross-linked to 35S pre-rRNA both in deproteinized extracts and
商品
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
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