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形狀
liquid
品質等級
濃度
100 mg/mL in DMSO
顏色
colorless to faint yellow
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
fungi
parasites
作用方式
DNA synthesis | interferes
運輸包裝
dry ice
儲存溫度
−20°C
InChI
1S/C14H18N4O3.C10H11N3O3S/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2-6H,11H2,1H3,(H,12,13)
InChI 密鑰
WZRJTRPJURQBRM-UHFFFAOYSA-N
相关类别
應用
复方新诺明已被用作抗菌剂。
生化／生理作用
复方新诺明是甲氧苄啶和磺胺甲恶唑的组合，可通过阻止核苷酸的生物合成来干扰叶酸在细菌细胞中的细胞代谢。甲氧苄啶与二氢叶酸还原酶（DHFR）结合，从而抑制二氢叶酸（DHF）还原为四氢叶酸（THF），从而产生抗菌作用。新诺明通过阻止对氨基苯甲酸向辅酶二氢叶酸的转化来干扰敏感微生物中核酸的合成。这些作用的最终结果是抑制胸腺嘧啶核苷的合成，从而阻止细菌 DNA 的合成。
包裝
1ml
準備報告
使用甲氧苄啶：磺胺甲恶唑的 1：5 混合物制备
其他說明
保存于密闭容器内，置于干燥通风处。
訊號詞
Warning
危險聲明
危險分類
Aquatic Chronic 3 - Repr. 2
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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