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生物源
rabbit
共軛
alkaline phosphatase conjugate
抗體表格
affinity isolated antibody
抗體產品種類
secondary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
baboon, monkey, marmoset
技術
direct ELISA: 1:40,000
dot blot: 1:60,000 (direct chemiluminescence assay)
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
一般說明
IgG (immunoglobulin G) antibody subtype is a predominant serum immunoglobulin of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. IgG is found in four subclasses IgG1, IgG2, IgG3 and IgG4. IgG has a monomeric structure.
IgGs are glycoprotein antibodies that modulate several immune responses. Serum IgG levels of rhesus monkeys are comparable to that of men, hence these monkeys are often used as models for studying immunological disorders. Thus, anti-monkey IgGs can be useful tools for the detection and localization of monkey IgGs. Anti-Monkey IgG (whole molecule)-Alkaline Phosphatase antibody binds to monkey, baboon and marmoset IgGs.
免疫原
Purified monkey IgG (rhesus)
應用
Alkaline phosphatase-conjugated rabbit anti-monkey IgG antibody has been used as a secondary antibody in enzyme linked immunsorbent assay (ELISA) to detect the level of IgG in serum from treated marmoset monkeys. It has also been used for western blot analysis of to identify maternal IgGs in serum from Rhesus monkeys after lentiviral gene transfer.
生化／生理作用
IgG antibody participates in complement fixation and opsonization.
外觀
Solution in 0.05 M Tris, pH 8.0, containing 1% bovine serum albumin, 1 mM MgCl2 and 15 mM sodium azide
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Stefano Colloca et al.
Science translational medicine, 4(115), 115ra2-115ra2 (2012-01-06)
Replication-defective adenovirus vectors based on human serotype 5 (Ad5) induce protective immune responses against diverse pathogens and cancer in animal models, as well as elicit robust and sustained cellular immunity in humans. However, most humans have neutralizing antibodies to Ad5
S J Challacombe et al.
Immunology, 36(2), 331-338 (1979-02-01)
Rhesus monkey IgG, IgA and IgM were purified from pooled normal serum and labelled with 125I. Four monkeys were injected intravenously with approximately 50 microgram of each purified immunoglobulin containing between 25 muCi and 50 muCi of 125I. Iodination was
M J Wolfgang et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(19), 10728-10732 (2001-09-13)
Transgenic mice have provided invaluable information about gene function and regulation. However, because of marked differences between rodents and primates, some areas of human biology such as early embryonic development, aging, and maternal-fetal interactions would be best studied in a
L Boon et al.
Journal of immunology (Baltimore, Md. : 1950), 167(5), 2942-2949 (2001-08-18)
Inhibition of CD40-CD40 ligand interaction is a potentially effective approach for treatment of autoimmune diseases, such as multiple sclerosis. We have investigated this concept with a chimeric antagonist anti-human CD40 mAb (ch5D12) in the marmoset monkey experimental autoimmune encephalomyelitis (EAE)
KISS1 over-expression suppresses metastasis of pancreatic adenocarcinoma in a xenograft mouse model.
Lacey R McNally et al.
Clinical & experimental metastasis, 27(8), 591-600 (2010-09-17)
Identifying molecular targets for treatment of pancreatic cancer metastasis is critical due to the high frequency of dissemination prior to diagnosis of this lethal disease. Because the KISS1 metastasis suppressor is expressed at reduced levels in advanced pancreatic cancer, we
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