58199
N-Lauroyl-D-sphingosine
≥98.0% (TLC)
别名:
Cer(d18:1/12:0), (2S,3R,4E)-2-(Lauroylamino)-4-octadecene-1,3-diol, N-Dodecanoyl-D-sphingosine, N-Lauroyl-D-erythro-sphingosine, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]dodecanamide, C12 Ceramide (d18:1/12:0), C12-Ceramide
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所有图片(1)
About This Item
经验公式（希尔记法）:
C30H59NO3
CAS号:
分子量:
481.79
Beilstein:
1717021
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
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化驗
≥98.0% (TLC)
成份
carbon content, 74.79%
hydrogen content, 12.34%
nitrogen content, 2.91%
脂質類型
sphingolipids
儲存溫度
−20°C
SMILES 字串
OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1
InChI 密鑰
HXFPPRPLRSPNIB-VARSQMIESA-N
包裝
Bottomless glass bottle. Contents are inside inserted fused cone.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
T Momoi et al.
The Biochemical journal, 205(2), 419-425 (1982-08-01)
The specific activity of acid ceramidase (N-acylsphingosine deacylase, EC 3.5.1.23) was measured at pH4.5 in normal fibroblasts and in fibroblasts from patients with Farber disease and obligate heterozygotes. Greater activity was found when the synthetically made ceramide substrates contained shorter-chain
Sandra Buratta et al.
PloS one, 12(11), e0188840-e0188840 (2017-11-29)
Cells release extracellular vesicles (EVs) in their environment and cellular lipids play an important role in their formation, secretion and uptake. Besides, there is also evidence that EV transferred lipids impact on recipient's cell signaling. Cellular senescence is characterized by
Jin Park et al.
Biochemical pharmacology, 71(8), 1229-1239 (2006-02-02)
Allergic diseases are hypersensitivity disorders that are associated with the generation of specific immunoglobulin E (IgE) in response to environmental allergens. Interleukin (IL)-4, which is primarily produced by the CD4(+) T cells, is an important stimulus for the switching of
G van Echten-Deckert et al.
Journal of lipid research, 38(12), 2569-2579 (1998-02-11)
De novo synthesis and turnover of endogenous ceramide in cultured skin fibroblasts from patients affected with Farber lipogranulomatosis were studied by biosynthetical labeling of cellular sphingolipids with [14C]serine. The cellular uptake of [14C]serine and incorporation into de novo synthesized ceramide
Eunice W M Chin et al.
Neuromolecular medicine, 18(3), 364-377 (2016-07-06)
Rett syndrome (RTT) is a postnatal neurodevelopmental disorder that primarily affects girls. Mutations in the methyl-CpG-binding protein 2 (MECP2) gene account for approximately 95 % of all RTT cases. To model RTT in vitro, we generated induced pluripotent stem cells (iPSCs)
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