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生物源
Bacillus brevis
化驗
~90% (HPLC)
形狀
powder
雜質
≤5% water
顏色
white to off-white
抗生素活性譜
Gram-negative bacteria
Gram-positive bacteria
作用方式
cell membrane | interferes
enzyme | inhibits
儲存溫度
2-8°C
SMILES 字串
CC(C)C[C@@H]1NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H](Cc5ccccc5)NC1=O)C(C)C)C(C)C
一般說明
Chemical structure: peptide
應用
Gramicidin is a naturally occuring polypeptide antibiotic. It functions as a transmembrane ion channel and is used for studies on phospholipid bilayer membrane fluidity measured by lateral diffusion.
生化/生理作用
Gramicidin′s bactericidal activity is a result of increasing the permeability of the bacterial cell membrane. This allows inorganic monovalent cations to travel through unrestricted which thereby destroys the ion gradient between the cytoplasm and the extracellular environment .
Naturally occuring polypeptide antibiotic with Tyr at position 11; functions as a transmembrane ion channel.
包裝
10mg
其他說明
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place. Keep in a dry place.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Anal. Profiles Drug Subst., 8, 179-179 (1979)
Yonsei medical journal, 49(3), 459-471 (2008-06-27)
This study examined the expression and function of inward rectifier K(+) channels in cultured rat hepatic stellate cells (HSC). The expression of inward rectifier K(+) channels was measured using real-time RT-PCR, and electrophysiological properties were determined using the gramicidin-perforated patch-clamp
Physiology and Pathology of Chloride Transporters and Channels in the Nervous System: From Molecules to Diseases.
Physiology and Pathology of Chloride Transporters and Channels in the Nervous System: From Molecules to Diseases, 142-142 (2009)
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