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Merck
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主要文件

490M-1

Tyrosine Hydroxylase (LNC1) Mouse Monoclonal Antibody

别名:

TYH

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About This Item

分類程式碼代碼:
41116161

生物源

(Mouse)

品質等級

共軛

unconjugated

抗體表格

(IgG1 Supernatant)

抗體產品種類

primary antibodies

無性繁殖

LNC1

描述

For In Vitro Diagnostic Use in Select Regions

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL (concentrate (490M-14))
vial of 0.1 mL (concentrate (490M-14-RUO) Research Use Only)
vial of 0.5 mL (concentrate (490M-15))
vial of 1.0 mL (concentrate (490M-16))
vial of 1.0 mL (concentrate (490M-16-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute (490M-17-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute ready-to-use (490M-17))
vial of 7.0 mL (pre-dilute ready-to-use (490M-18))
vial of 7.0 mL (pre-dilute ready-to-use (490M-18-RUO) Research Use Only)

製造商/商標名

Cell Marque®

技術

immunohistochemistry: suitable (formalin-fixed, paraffin-embedded sections 1:25-1:100 (concentrated))

同型

IgG1

控制

neuroblastoma

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic

一般說明

Tyrosine Hydroxylase (TYH) is the rate-limiting enzyme of catecholamine biosynthesiss. TYH uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-DOPA, a precursor to dopamine. Anti-TYH is sensitive and specific for peripheral neuroblastic tumors in the differential diagnosis from other tumors of childhood and shows high diagnostic utility. Anti-TYH has been shown to positively label all pheochromocytomas and sympathetic paragangliomas, and thus aids in differentiating them from their histologic mimics such as adrenocortical neoplasms.

品質

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Junkichi Takemoto et al.
Human pathology, 85, 162-167 (2018-11-24)
The RNA-binding protein HuC/D displays a neuron-specific expression and is involved in neuronal differentiation and the maintenance of the nervous system. Here we investigated the diagnostic value of HuC/D in neuroblastomas. We evaluated 85 neuroblastic tumors: 81 neuroblastomas; 3 ganglioneuroblastomas
L A Loizou
British journal of pharmacology, 41(1), 41-48 (1971-01-01)
1. Tyrosine hydroxylase is thought to be the rate limiting enzyme step in catecholamine biosynthesis. Inhibition of this enzyme using alpha-methyl-p-tyrosine resulted in a time dependent depletion (and repletion) of formaldehyde induced fluorescence in catecholamine-containing neurones of the central nervous

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