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Merck
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主要文件

445R-1

Sigma-Aldrich

NKX2.2 (EP336) Rabbit Monoclonal Primary Antibody

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP336, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (445R-14)
vial of 0.1 mL concentrate Research Use Only (445R-14-RUO)
vial of 0.5 mL concentrate (445R-15)
vial of 1.0 mL concentrate (445R-16)
vial of 1.0 mL concentrate Research Use Only (445R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (445R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (445R-17)
vial of 7.0 mL pre-dilute ready-to-use (445R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (445R-18-RUO)

製造商／商標名

Cell Marque™

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

同型

IgG

控制

Ewing’s sarcoma, pancreas

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

nuclear

相关类别

一般說明

NKX2.2 is a homeodomain transcription factor that plays a role in neuroendocrine and glial differentiation. NKX2.2 is upregulated in Ewing′s sarcoma as a result of the oncogenic EWS-FLI1 fusion protein. As one of many small round blue cell tumors, Ewing′s sarcoma can be difficult to diagnose due to the characteristic undifferentiated morphology. NKX2.2 has proven its utility as a sensitive maker for distinguishing Ewing′s sarcoma from other round blue cell tumors when used in a panel.

品質


IVD
IVD
IVD
RUO

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

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其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析证书(COA)

Lot/Batch Number
0000299062
0000299062

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Arvind Rajwanshi et al.
Journal of cytology, 26(1), 1-10 (2009-01-01)
Malignant small round cell tumors are characterised by small, round, relatively undifferentiated cells. They generally include Ewing's sarcoma, peripheral neuroectodermal tumor, rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma, retinoblastoma, neuroblastoma, hepatoblastoma, and nephroblastoma or Wilms' tumor. Other differential diagnoses of small round
Yoshinari Yamamoto et al.
Journal of cytology, 32(1), 30-32 (2015-05-08)
Renal Ewing sarcoma (ES) is a rare malignant tumor characterized by fusion of the EWSR1 gene with a member of the ETS family of oncogenes, arising at a specific chromosomal translocation. Diagnosis of ES can be problematic, especially from cytological
Akihiko Yoshida et al.
The American journal of surgical pathology, 36(7), 993-999 (2012-03-27)
Ewing sarcoma is a high-grade round cell sarcoma that affects bones and soft tissues in children and young adults. Its diagnosis can be challenging, and the differential diagnoses include a wide variety of small round cell tumors. CD99 and FLI-1

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