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Merck
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Key Documents

441R-1

Sigma-Aldrich

NKX3.1 (EP356) Rabbit Monoclonal Primary Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP356, monoclonal

描述

(For In Vitro Diagnostic Use in Select Regions (See Chart))

形狀

buffered aqueous solution

物種活性

human

包裝

bottle of 1.0 mL predilute (441R-17)
bottle of 7.0 mL predilute (441R-18)
vial of 0.1 mL concentrate (441R-14)
vial of 0.5 mL concentrate (441R-15)
vial of 1.0 mL concentrate (441R-16)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

同型

IgG

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

human ... NKX3-1(4824)

一般說明

NKX3.1 is a prostate-specific androgen-regulated homeobox gene located on chromosome8p.1-2 NKX3.1 expression is seen in benign and malignant prostate epithelium. NKX3.1is a sensitive and specific tissue marker that can be used to help identify prostateadenocarcinoma.

品質


IVD

IVD

IVD

RUO

聯結

NKX3.1 Positive Control Slides, Product No. 441S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Rebecca J Asch-Kendrick et al.
Journal of clinical pathology, 67(9), 768-771 (2014-07-06)
NKX3.1 is an androgen-regulated tumour suppressor gene that is downregulated in prostate carcinoma. Immunohistochemistry for NKX3.1 is primarily specific for prostatic-derived tumours and tissue but is reported in a small number of breast carcinomas. NKX3.1 is also shown to inhibit
Ai-Ying Chuang et al.
The American journal of surgical pathology, 31(8), 1246-1255 (2007-08-02)
The histologic distinction between high-grade prostate cancer and infiltrating high-grade urothelial cancer may be difficult, and has significant implications because each disease may be treated very differently (ie, hormone therapy for prostate cancer and chemotherapy for urothelial cancer). Immunohistochemistry of
Bora Gurel et al.
The American journal of surgical pathology, 34(8), 1097-1105 (2010-07-01)
NKX3.1 is a prostatic tumor suppressor gene located on chromosome 8p. Although most studies have shown that staining for NKX3.1 protein is positive in the majority of primary prostatic adenocarcinomas, it has been shown to be downregulated in many high-grade

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