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Merck
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主要文件

338A-7

Sigma-Aldrich

TdT Rabbit Polyclonal Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

Ig fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (338A-74)
vial of 0.5 mL concentrate (338A-75)
bottle of 1.0 mL predilute (338A-77)
vial of 1.0 mL concentrate (338A-76)
bottle of 7.0 mL predilute (338A-78)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

控制

thymus

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

nuclear

基因資訊

human ... DNTT(1791)

一般說明

TdT (terminal deoxynucleotidyl transferase) is a template-independent DNA polymerasethat adds nucleotides randomly to single-stranded DNA. This randomization plays a role inacquired immunity by increasing antigen receptor diversity and aiding in the generation ofimmunoglobulins and T-cell antigen receptors. TdT immunoreactivity is observed mainly in the thymus. Anti-TdT is often used to visualize lymphoblastic lymphomas and has also beenobserved in some cases of acute myeloid leukemia.

品質


IVD

IVD

IVD

RUO

聯結

TdT Positive Control Slides, Product No. 338S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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R C Mathewson et al.
Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association, 17(6), 835-844 (1997-11-14)
In the differential diagnosis of small round cell tumors (SRCTs), terminal deoxynucleotidyl transferase (TdT) is often used as a marker for lymphoblastic lymphomas and leukemias. However, the specificity of TdT using the avidin-biotin-immunoperoxidase (ABC) method is not well documented. To
M Ozdemirli et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 14(11), 1175-1182 (2001-11-14)
We encountered a child with an intraosseous small round cell tumor that was negative for LCA, CD20 (L26), and CD3 and positive for vimentin, CD99 (MIC-2), and periodic acid-Schiff. The tumor exhibited rosette-like formations. This case was initially interpreted as
A Practical Approach to Diagnosis, 312-316 (1990)
R A Soslow et al.
Human pathology, 28(10), 1158-1165 (1997-10-29)
We propose that 12E7 (CD99) expression, along with TdT, bcl-2, and CD34 reactivity in lymphoblastic lymphoma (LyL)/acute lymphoblastic leukemia (ALL), distinguishes this group of neoplasms from small noncleaved cell lymphomas (SNCLs) in both pediatric and adult patients, thereby narrowing the
Ewing sarcoma vs lymphoblastic leukemia.
S Hirschl
American journal of clinical pathology, 115(6), 933-934 (2001-06-08)

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