321R-2

PLAP (EP194) Rabbit Monoclonal Primary Antibody

• 别名: Placental Alkaline Phosphatase
• 分類程式碼代碼: 12352203

属性

• 生物源: rabbit
• 共軛: unconjugated
• 抗體表格: culture supernatant
• 抗體產品種類: primary antibodies
• 無性繁殖: EP194, monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions
• 形狀: buffered aqueous solution
• 物種活性: human
• 包裝: vial of 0.1 mL concentrate (321R-24); vial of 0.1 mL concentrate Research Use Only (321R-24-RUO); vial of 0.5 mL concentrate (321R-25); vial of 1.0 mL concentrate (321R-26); vial of 1.0 mL concentrate Research Use Only (321R-26-RUO); vial of 1.0 mL pre-dilute Research Use Only (321R-27-RUO); vial of 1.0 mL pre-dilute ready-to-use (321R-27); vial of 7.0 mL pre-dilute ready-to-use (321R-28); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (321R-28-RUO)
• 製造商／商標名: Cell Marque^™
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• 同型: IgG
• 控制: placenta
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 視覺化: cytoplasmic
• 基因資訊: human ... ALPP(250)

说明

一般說明

Placental alkaline phosphatase (PLAP) is normally produced by primordial germ cells and syncytiotrophoblasts, and the detection of its expression has been useful in identifying germ cell tumors. Anti-PLAP antibody immunoreacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease. Complete hydatidiform mole shows strong expression of hCG and weak expression of PLAP. Weak hCG and strong PLAP expression is found in partial hydatidiform mole. Choriocarcinoma presents strong expression of hCG and weak expression of hPL and PLAP.8 In addition to its role as a germ cell marker, PLAP may also be used as a myogenic marker in identifying soft tissue tumors.

品質

IVD

IVD

IVD

RUO

聯結

PLAP Positive Control Slides, Product No. 321S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

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其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable