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Merck
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主要文件

298R-1

Sigma-Aldrich

Myosin, Smooth Muscle (EP166) Rabbit Monoclonal Primary Antibody

别名:

Smooth Muscle Myosin, heavy chain (SMM-HC)

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About This Item

分類程式碼代碼:
12352203

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP166, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (298R-14)
vial of 0.1 mL concentrate Research Use Only (298R-14-RUO)
vial of 0.5 mL concentrate (298R-15)
vial of 1.0 mL concentrate (298R-16)
vial of 1.0 mL concentrate Research Use Only (298R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (298R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (298R-17)
vial of 7.0 mL pre-dilute ready-to-use (298R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (298R-18-RUO)

製造商/商標名

Cell Marque®

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

同型

IgG

控制

breast

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic

基因資訊

human ... MYH11(4629)

一般說明

Smooth Muscle Myosin, heavy chain (SMM-HC) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. SMM-HC is also a myoepithelium-associated protein. Anti-SMM-HC is a monoclonal antibody to smooth muscle myosin, heavy chain that reacts with human visceral and vascular smooth muscle cells. The antibody also reacts with human myoepithelial cells. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.

品質


IVD

IVD

IVD

RUO

聯結

Myosin, Smooth Muscle Positive Control Slides, Product No. 298S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Download the latest released IFU
Note: This IFU may not apply to your specific product lot.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Robert W Werling et al.
The American journal of surgical pathology, 27(1), 82-90 (2002-12-28)
Identification of myoepithelial cells using antibodies to cytoskeletal proteins, such as smooth muscle myosin heavy chain (SMM-HC) and calponin, can play an important role in distinguishing invasive carcinoma from its histologic mimics. However, antibodies to these proteins may also cross-react
D Lazard et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(3), 999-1003 (1993-02-01)
The expression of several differentiation markers in normal human mammary gland myoepithelium and in certain stromal fibroblasts ("myofibroblasts") associated with breast carcinomas was studied by immunofluorescence microscopy of frozen sections. Several antibodies to smooth muscle-specific proteins (smooth muscle alpha-actin, smooth

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