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Merck
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主要文件

231R-1

Sigma-Aldrich

Calponin-1 (EP798Y) Rabbit Monoclonal Primary Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP798Y, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (231R-14)
vial of 0.5 mL concentrate (231R-15)
bottle of 1.0 mL predilute (231R-17)
vial of 1.0 mL concentrate (231R-16)
bottle of 7.0 mL predilute (231R-18)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

同型

IgG

控制

appendix

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic

一般說明

Calponin is a 34-kD polypeptide that interacts with actin, tropomyosin, and calmodulin. Itis involved in the smooth muscle contraction mechanism and is restricted exclusively to smoothmuscle tissue. Anti-calponin has been found to be useful in staining myoepithelium and thushas been used to confirm the presence of myoepithelial cells in benign breast proliferationand their absence in invasive breast carcinomas. Calponin positivity has also been noted inmyoepithelial neoplasms and pleomorphic adenoma of the salivary gland.

品質


IVD

IVD

IVD

RUO

聯結

Calponin Positive Control Slides, Product No. 231S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Antibodies to novel myoepithelium-associated proteins distinguish benign lesions and carcinoma in situ from invasive carcinoma of the breast
Wang NP, et al.
Appl. Immunohistochem., 5, 141-151 (1997)
Cheryl B Hill et al.
American journal of clinical pathology, 123(1), 36-44 (2005-03-15)
We evaluated 25 intraductal papillomas and 18 papillary carcinomas (invasive, 4; micropapillary ductal carcinoma in situ [DCIS], 5; cases originally classified as intracystic/intraductal papillary carcinoma, 9) by calponin, smooth muscle myosin heavy chain (SMM-HC), and p63 immunostains. Calponin, SMM-HC, and
J C Fanburg-Smith et al.
Human pathology, 30(11), 1336-1343 (1999-11-26)
Angiomatoid "malignant" fibrous histiocytoma (AMFH) has been considered to be a low-grade sarcoma of childhood, and, with its fibrous pseudocapsule, angiomatoid change, dense lymphoplasmacytic response, and proliferation of spindled or round cells, has been classified as a fibrohistiocytic neoplasm. We
A T Savera et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 10(11), 1093-1100 (1997-12-05)
Myoepithelial cells of salivary glands have a complex cytoskeletal immunophenotype. To elaborate the smooth muscle phenotype of salivary gland myoepithelium and to assess its contribution to the histogenesis of pleomorphic adenomas, we evaluated the immunohistochemical expression of three novel monoclonal
T Nagao et al.
Cancer, 83(7), 1292-1299 (1998-10-08)
Malignant myoepithelioma (MME) of the salivary gland, also known as myoepithelial carcinoma, is rare and its biologic behavior has not been clarified fully. Ten cases of MME were analyzed for their clinicopathologic features and immunohistochemical characteristics, focusing on prognostic factors

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