推荐产品
生物源
mouse
品質等級
100
500
共軛
unconjugated
抗體表格
culture supernatant
抗體產品種類
primary antibodies
無性繁殖
ALK-1, monoclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (204M-14)
vial of 0.5 mL concentrate (204M-15)
bottle of 1.0 mL predilute (204M-17)
vial of 1.0 mL concentrate (204M-16)
bottle of 7.0 mL predilute (204M-18)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
同型
IgG3κ
控制
anaplastic large cell lymphoma
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic, nuclear
一般說明
ALK-1 is a novel fusion protein which is detected in 60% of Anaplastic Large Cell Lymphomas and has proven to indicate improved prognosis in the ALK-1 (+) group.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
ALK Protein Positive Control Slides, Product No. 204S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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B Falini et al.
The American journal of pathology, 153(3), 875-886 (1998-09-15)
The t(2;5)(p23;q35) translocation associated with CD30-positive anaplastic large cell lymphoma results in the production of a NPM-ALK chimeric protein, consisting of the N-terminal portion of the NPM protein joined to the entire cytoplasmic domain of the neural receptor tyrosine kinase
S Nakamura et al.
The American journal of surgical pathology, 21(12), 1420-1432 (1997-12-31)
The p80(NPM/ALK) expression activated by the t(2;5) (p23;q35) translocation recently has been shown to play an important role in the pathogenesis of anaplastic large cell lymphoma (ALCL). However, the clinicopathologic significance of identification of p80 among ALCL cases has not
K A Cataldo et al.
The American journal of surgical pathology, 23(11), 1386-1392 (1999-11-11)
Anaplastic large cell lymphoma (ALCL) is associated with the t(2;5)(p23;q35) translocation involving the anaplastic lymphoma kinase gene (ALK) and the nucleophosmin gene (NPM), which result in expression of a novel fusion protein, NPM-ALK (p80). Clinicopathologic studies have shown that ALK
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