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Merck

14479

Sigma-Aldrich

Phalloidin-Atto 490LS

suitable for fluorescence

别名:

Atto 490LS-Phalloidin

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About This Item

分類程式碼代碼:
12352108
NACRES:
NA.32

化驗

≥75.0% (HPLC)

分子量

Mw 1466 g/mol

製造商/商標名

ATTO-TEC GmbH

&lambda ;

in acetonitrile: water (1:1)

紫外吸收

λ: 495-501 nm Amax

適合性

suitable for fluorescence

儲存溫度

−20°C

一般說明

Atto 490LS is a new fluorescent label featuring an extraordinary large Stokes-Shift of 165 nm. Thus the emission spectrum is almost completely separated from its absorption spectrum, making the dye highly suitable for multiplexing experiments, in particular in combination with Atto 488 and Atto 514. Atto 490LS is very hydrophillic and shows excellent water solubility. The dye exhibits a relatively high fluorescence quantum yield, which is only slightly reduced after conjugation to biomolecules, e.g. proteins, even at high degrees of labeling (DOL). Atto 490LS is an anionic dye. After conjugation to a substrate the dye carries a net electrical charge of -1.
Phalloidin, a bicyclic heptapeptide, is a very strong binding reagent to actin. Fluorescent labeled phalloidin has become a useful tool to investigate the distribution of F-actin within the cytoskeleton of cells by fluorescence microscopy.

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法律資訊

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Xiaomeng Zhang et al.
Oncogene, 39(30), 5267-5281 (2020-06-21)
Melanoma is a deadly form of skin cancer that accounts for a disproportionally large proportion of cancer-related deaths in younger people. Compared with most other skin cancers, a feature of melanoma is its high metastatic capacity, although the mechanisms that

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