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Merck

71778

Sigma-Aldrich

硝普钠 二水合物

puriss. p.a., ACS reagent, reag. Ph. Eur., ≥99%

别名:

SNP, 五氰基亚硝酰基铁酸钠, 亚硝基铁氰化钠, 硝普酸钠

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About This Item

线性分子式:
Na2[Fe(CN)5NO] · 2H2O
CAS号:
分子量:
297.95
EC號碼:
MDL號碼:
分類程式碼代碼:
12352300
PubChem物質ID:
NACRES:
NB.24

等級

ACS reagent
puriss. p.a.

品質等級

agency

reag. Ph. Eur.
suitable for SM 4500 - NH3

化驗

≥99%

形狀

crystals or chunks

溶解度

water: soluble(lit.)

負離子痕跡

chloride (Cl-): ≤100 mg/kg
hexacyanoferrate(II) ([Fe(CN)6]4-): ≤200 mg/kg
hexacyanoferrate(III) ([Fe(CN)6]3-): ≤100 mg/kg
sulfate (SO42-): ≤100 mg/kg

正離子痕跡

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤50 mg/kg
Cu: ≤5 mg/kg
K: ≤3000 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤50 mg/kg

SMILES 字串

O.O.[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N

InChI

1S/5CN.Fe.NO.2Na.2H2O/c5*1-2;;1-2;;;;/h;;;;;;;;;2*1H2/q;;;;;2*-1;2*+1;;

InChI 密鑰

OIRZWVYIQXBRFC-UHFFFAOYSA-N

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一般說明

硝普钠二水合物(五氰基亚硝酰基铁(2-)酸钠二水合物,SNP)分子含有一个亚铁离子中心,其被五个氰化物基团和亚硝酰基包围。硝普钠具有临床应用价值。它可用作一种快速起效的血管扩张剂。它还被广泛用作各种实验模型的一氧化氮(NO)供体。已经鉴定了硝普钠二水合物Na2[Fe(CN)5NO].2H2O的两种亚稳态,并且已通过X射线衍射研究了它们的几何形状。

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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M Chiusa et al.
European journal of histochemistry : EJH, 56(2), e15-e15 (2012-06-13)
Sodium nitroprusside (SNP) is used clinically as a rapid-acting vasodilator and in experimental models as donor of nitric oxide (NO). High concentrations of NO have been reported to induce cardiotoxic effects including apoptosis by the formation of reactive oxygen species.
Aamer Sandoo et al.
Arthritis research & therapy, 13(3), R99-R99 (2011-06-23)
Patients with rheumatoid arthritis (RA) are at an increased risk for cardiovascular disease (CVD). One of the earliest manifestations of CVD is endothelial dysfunction (ED). ED can occur in both the microcirculation and the macrocirculation, and these manifestations might be
Diffraction studies of photoexcited crystals: Metastable nitrosyl-linkage isomers of sodium nitroprusside.
Carducci MD, et al.
Journal of the American Chemical Society, 119(11), 2669-2678 (1997)
Jae Hyung Kim et al.
Journal of applied physiology (Bethesda, Md. : 1985), 107(4), 1249-1257 (2009-08-08)
There is increasing evidence that upregulation of arginase contributes to impaired endothelial function in aging. In this study, we demonstrate that arginase upregulation leads to endothelial nitric oxide synthase (eNOS) uncoupling and that in vivo chronic inhibition of arginase restores
Brittany G Durgin et al.
JCI insight, 4(19) (2019-09-06)
Nitric oxide regulates BP by binding the reduced heme iron (Fe2+) in soluble guanylyl cyclase (sGC) and relaxing vascular smooth muscle cells (SMCs). We previously showed that sGC heme iron reduction (Fe3+ → Fe2+) is modulated by cytochrome b5 reductase

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