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Key Documents

Y0001832

Irinotecan hydrochloride trihydrate

European Pharmacopoeia (EP) Reference Standard

别名:

Irinotecan monohydrochloride trihydrate, [1,4′-Bipiperidine]-1′-carboxylic acid (S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester monohydrochloride trihydrate

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About This Item

经验公式(希尔记法):
C33H38N4O6 · HCl · 3H2O
分子量:
677.18
分類程式碼代碼:
41116107
NACRES:
NA.24

API 家族

irinotecan

儲存溫度

2-8°C

InChI

1S/C33H38N4O6.ClH.3H2O/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2;;;;/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3;1H;3*1H2/t33-;;;;/m0..../s1

InChI 密鑰

KLEAIHJJLUAXIQ-JDRGBKBRSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

包裝

Unit quantity: 170 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

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Inhibition of intestinal microflora ?-glucuronidase modifies the distribution of the active metabolite of the antitumor agent, irinotecan hydrochloride (CPT-11) in rats.
Takasuna K, et al.
Cancer Chemotherapy and Pharmacology, 42(4), 280-286 (1998)
Simultaneous determination of irinotecan hydrochloride and its related compounds by high performance liquid chromatography using ultraviolet detection.
Mohammadi A.
Asian Journal of Chemistry, 22(5), 3966-3966 (2010)

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