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Y0000489

霉酚酸酯

Name: 霉酚酸酯
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

(4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester, RS 61443, TM-MMF

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About This Item

经验公式（希尔记法）:

C₂₃H₃₁NO₇

CAS号:

128794-94-5

分子量:

433.49

MDL號碼:

MFCD00867568

分類程式碼代碼:

41116107

PubChem物質ID:

329830980

NACRES:

NA.24

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Millipore

VT000096

Enterococcus faecalis WDCM 00009 Vitroids^™

Y0000519

吗替麦考酚酯

Supelco

PHR1451

霉酚酸酯

Millipore

VT001793

Escherichia coli WDCM 00179 Vitroids^™

Supelco

PHR3211

Mycophenolate Sodium

Sigma-Aldrich

SML0284

霉酚酸酯

Millipore

VT000092

Enterococcus faecalis WDCM 00009 Vitroids^™

Y0002200

Mycophenolate for system suitability

BP1254

霉酚酸酯

USP

1448956

霉酚酸酯

等級

pharmaceutical primary standard

API 家族

mycophenolate

製造商／商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)OCCN3CCOCC3

InChI

1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+

InChI 密鑰

RTGDFNSFWBGLEC-SYZQJQIISA-N

基因資訊

human ... IMPDH1(3614) , IMPDH2(3615)

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Mycophenolate mofetil EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化／生理作用

Mycophenolate mofetil is a prodrug of mycophenolic acid (Cat. # M5255) that is cleaved by nonspecific esterases in vivo to produce the parent compound. Mycophenolic acid blocks inosine monophosphate dehydrogenase and is a potent immunosuppresive agent.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

訊號詞

Danger

危險聲明

H302,H360D,H372,H410

防範說明

P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析证书(COA)

Lot/Batch Number

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To investigate the efficacy and safety of ocrelizumab in patients with class III/IV lupus nephritis (LN). Patients were randomized 1:1:1 to receive placebo, 400 mg ocrelizumab, or 1,000 mg ocrelizumab given as an intravenous infusion on days 1 and 15

Outcomes of pancreas retransplantation after simultaneous kidney-pancreas transplantation are comparable to pancreas after kidney transplantation alone.

John Seal et al.

Transplantation, 99(3), 623-628 (2014-08-26)

There is a paucity of contemporary data describing the results of pancreas retransplantation (PRT). As a measure of utility, we wished to determine whether PRT could produce equivalent short-term and long-term recipient outcomes to primary pancreas after kidney (PAK) transplantation.

Novel once-daily extended-release tacrolimus (LCPT) versus twice-daily tacrolimus in de novo kidney transplants: one-year results of Phase III, double-blind, randomized trial.

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American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 14(12), 2796-2806 (2014-10-04)

This Phase III randomized trial examined efficacy and safety of a novel once-daily extended-release tacrolimus formulation (LCP-Tacro [LCPT]) versus twice-daily tacrolimus in de novo kidney transplantation. Primary efficacy end point was proportion of patients with treatment failure (death, graft failure

Histologic features in colon biopsies can discriminate mycophenolate from GVHD-induced colitis.

Kremena V Star et al.

The American journal of surgical pathology, 37(9), 1319-1328 (2013-10-01)

Mycophenolate mofetil (MMF) is a T-cell inhibitor frequently used in the treatment of acute allograft rejection. MMF may cause colitis that clinically and histologically resembles graft-versus-host disease (GVHD). The aim of this study was to evaluate a wide range of

Screening for new-onset diabetes after kidney transplantation: limitations of fasting glucose and advantages of afternoon glucose and glycated hemoglobin.

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Key Documents

霉酚酸酯

European Pharmacopoeia (EP) Reference Standard

About This Item

推荐产品

属性

等級

API 家族

製造商／商標名

應用

格式

儲存溫度

SMILES 字串

InChI

InChI 密鑰

基因資訊

相关类别

说明

一般說明

應用

生化／生理作用

包裝

其他說明

相关产品

相關產品

安全信息

象形圖

訊號詞

危險聲明

防範說明

危險分類

儲存類別代碼

水污染物質分類（WGK）

閃點（°F）

閃點（°C）

文件

分析证书(COA)

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