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Merck

PHR1816

Supelco

呋塞米相关化合物B

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

4-氯-5-氨磺酰邻氨基苯甲酸

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About This Item

经验公式(希尔记法):
C7H7ClN2O4S
CAS号:
分子量:
250.66
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to USP 1287030

API 家族

furosemide

CofA

current certificate can be downloaded

包裝

pkg of 100 mg

mp

267 °C (dec.) (lit.)

應用

pharmaceutical

格式

neat

儲存溫度

2-30°C

SMILES 字串

Nc1cc(Cl)c(cc1C(O)=O)S(N)(=O)=O

InChI

1S/C7H7ClN2O4S/c8-4-2-5(9)3(7(11)12)1-6(4)15(10,13)14/h1-2H,9H2,(H,11,12)(H2,10,13,14)

InChI 密鑰

QQLJBZFXGDHSRU-UHFFFAOYSA-N

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一般說明

Furosemide Related Compound B is an impurity of the loop diuretic drug, furosemide. Furosemide is generally used to treat fluid retention in people with heart failure, liver cirrhosis or kidney disease.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Furosemide Related Compound B may be used as a reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC2893 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

象形圖

Environment

危險聲明

防範說明

危險分類

Aquatic Chronic 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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访问文档库

The analysis of 4-chloro-5-sulfamoylanthranilic acid in the bulk material and pharmaceutical preparations of furosemide by a high-performance liquid chromatographic method
Rapaka RS, et al.
International Journal of Pharmaceutics, 11(3), 237- 247 (1982)
Furosemide
StatPearls [Internet] (2019)
Furosemide
USP42/NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 41(3), 2006-2006 (2018)

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