PHR1341

糖精钠

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 糖精, 2,3-二羟基-1,2-苯并异噻唑基-3-酮-1,1-二氧化物, 2-磺基苯甲酸亚胺, 邻磺酰苯酰亚胺
• 经验公式（希尔记法）: C₇H₅NO₃S
• CAS号: 81-07-2
• 分子量: 183.18
• Beilstein: 6888
• EC號碼: 201-321-0
• MDL號碼: MFCD00005866
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823326
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to Ph. Eur. S0040000; traceable to USP 1607007
• API 家族: saccharin
• CofA: current certificate can be downloaded
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• mp: 226-229 °C (lit.)
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: O=C1NS(=O)(=O)c2ccccc12
• InChI: 1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
• InChI 密鑰: CVHZOJJKTDOEJC-UHFFFAOYSA-N

说明

一般說明

Saccharin is a well-known non-carbohydrate, sulfonyl amide artificial sweetener and is generally used in the form of its calcium or sodium salt. It possesses a sweetening power of about 550 times more than that of saccharose. On losing the acidic imino hydrogen, it forms the corresponding nitro anion, which exhibits interesting coordination chemistry. It offers a bitter and metallic aftertaste which limits its use as an artificial sweetening agent.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.

應用

Saccharin can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

哺乳动物的甜促味剂。有人提出，果蝇具有葡萄糖特异性甘油味觉受体结合位点。

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC3561 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable