等級
certified reference material
pharmaceutical secondary standard
品質等級
agency
traceable to USP 1601805
蒸汽密度
3.2 (vs air)
蒸汽壓力
22 mmHg ( 20 °C)
26 mmHg ( 25 °C)
CofA
current certificate can be downloaded
自燃溫度
997 °F
expl. lim.
7 %
技術
HPLC: suitable
gas chromatography (GC): suitable
折射率
n/D 1.496 (lit.)
bp
110-111 °C (lit.)
mp
-93 °C (lit.)
密度
0.865 g/mL at 25 °C (lit.)
應用
pharmaceutical (small molecule)
格式
neat
儲存溫度
2-30°C
SMILES 字串
Cc1ccccc1
InChI
1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3
InChI 密鑰
YXFVVABEGXRONW-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
一般說明
Toluene is a non-polar organic solvent and methyl derivative of benzene. As per USP and EP, it belongs to the Class 2 category of organic solvents and has limited application in the synthesis of pharmaceuticals, due to its moderate toxicity.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
應用
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Toluene may be used as a pharmaceutical solvent reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by gas chromatography.
分析報告
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
其他說明
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
腳註
To see an example of a Certificate of Analysis for this material enter LRAC2115 in the slot below. This is an example certificate only and may not be the lot that you receive.
推薦產品
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
訊號詞
Danger
危險分類
Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
39.9 °F
閃點(°C)
4.4 °C
其他客户在看
5.4 Residual Solvents
European pharmacopoeia, 5553-5560 (2018)
?467? Residual Solvents
United States Pharmacopeia/National Formulary, 45(3), 6712-6712 (2019)
Organic solvents in the pharmaceutical industry
Acta Poloniae Pharmaceutica, 67(1), 3-12 (2010)
A generic static headspace gas chromatography method for determination of residual solvents in drug substance.
Journal of Chromatography A, 1217(41), 6413-6421 (2010)
Journal of medicinal chemistry, 56(12), 4870-4879 (2013-05-29)
This study demonstrates that ΔlogP(oct-tol) (difference between logP(octanol) and logP(toluene)) describes compounds propensity to form intramolecular hydrogen bonds (IMHB) and may be considered a privileged molecular descriptor for use in drug discovery and for prediction of IMHB in drug candidates.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门