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等級
certified reference material
pharmaceutical secondary standard
品質等級
agency
traceable to Ph. Eur. B1212000
traceable to USP 1083008
蒸汽密度
6.2 (vs air)
API 家族
butylhydroxyanisole
CofA
current certificate can be downloaded
自燃溫度
599 °F
技術
HPLC: suitable
gas chromatography (GC): suitable
mp
58-60 °C (lit.)
應用
pharmaceutical (small molecule)
形式
neat
儲存溫度
2-30°C
InChI
1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3
InChI 密鑰
MRBKEAMVRSLQPH-UHFFFAOYSA-N
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一般說明
用于质量控制的制药二级标准品，为制药实验室和制造商制备内部工作标准品提供了一种方便、高性价比的替代方案。
應用
丁基羟基苯甲醚(BHA)可用作参考标准品，用于通过分光光度测定法测定药膏中的分析物。
这些二级标准品是合格的认证标准物质（CRM）。它们适用于多种分析应用，包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他校准需求。
分析報告
这些二级标准品可追溯至USP、EP（PhEur）和BP一级标准品。
其他說明
该认证参考物质（CRM）根据ISO 17034 和 ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。
腳註
要查看该材料的分析证书示例，请在下面的栏位中输入LRAB3751。这只是一个示例证书，可能不是您收到的批次。
危險聲明
危險分類
Aquatic Chronic 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
241.9 °F - Pensky-Martens closed cup
閃點（°C）
116.6 °C - Pensky-Martens closed cup
其他客户在看
Determination of miconazole in pharmaceutical creams using internal standard and second derivative spectrophotometry.
Wrobel K, et al.
Journal of Pharmaceutical and Biomedical Analysis, 20(1-2), 99-105 (1999)
[Modification of the processes of chemical mutagenesis and carcinogenesis by synthetic phenol antioxidants such as butylated hydroxyanisole].
K Demkowicz-Dobrzański et al.
Postepy biochemii, 38(1), 37-42 (1992-01-01)
H Verhagen et al.
Chemico-biological interactions, 80(2), 109-134 (1991-01-01)
Butylated hydroxyanisole (BHA) is a synthetic food antioxidant used to prevent oils, fats and shortenings from oxidative deterioration and rancidity. This review depicts the current knowledge on BHA. The physical and chemical characteristics of BHA are summarized and its function
J Whysner et al.
Pharmacology & therapeutics, 71(1-2), 137-151 (1996-01-01)
Butylated hydroxyanisole (BHA), at high doses, has been found to induce forestomach squamous cell carcinomas in rodents, but not glandular cell or other types of neoplasms. BHA is not DNA-reactive, and the epigenetic mechanism of tumor formation involves cytotoxicity and
G M Williams
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 24(10-11), 1163-1166 (1986-10-01)
Studies on the potential genotoxicity and epigenetic effects of BHA are reviewed. BHA was not DNA-reactive, but studies showed that it did have an effect on membrane systems, blocking exchange between hepatocytes and epithelial cells. The available data strongly suggest
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