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Merck

PHR1083

Supelco

奥克立林

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

2-氰基-3,3-二苯基-2-丙烯酸-2-乙己酯, OC

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About This Item

线性分子式:
(C6H5)2C=C(CN)CO2CH2CH(C2H5)(CH2)3CH3
CAS号:
分子量:
361.48
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to USP 1477411

API 家族

octocrylene

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

折射率

n20/D 1.567 (lit.)

bp

218 °C/1.5 mmHg (lit.)

mp

−10 °C (lit.)

密度

1.051 g/mL at 25 °C (lit.)

應用

environmental
pharmaceutical (small molecule)

形式

neat

儲存溫度

2-30°C

SMILES 字串

CCCCC(CC)COC(=O)\C(C#N)=C(/c1ccccc1)c2ccccc2

InChI

1S/C24H27NO2/c1-3-5-12-19(4-2)18-27-24(26)22(17-25)23(20-13-8-6-9-14-20)21-15-10-7-11-16-21/h6-11,13-16,19H,3-5,12,18H2,1-2H3

InChI 密鑰

FMJSMJQBSVNSBF-UHFFFAOYSA-N

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一般說明

制药二级标准用于质量控制,为制药实验室和制造商提供了一种方便、经济的内部工作标准编制替代方案。

應用

奥克立林可用作药物参考标准品,通过色谱技术测定药物制剂中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他标定应用。

分析報告

这些二级标准品可多次溯源至美国药典、欧洲药典和英国药典一级标准品(如可用)。

其他說明

该认证标准物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

腳註

要查看该材料的检验报告示例,请在下面的栏位中输入 LRAC0433。这只是一个示例证书,可能不是您收到的批次。

象形圖

Environment

訊號詞

Warning

危險聲明

防範說明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

453.2 °F - closed cup

閃點(°C)

234 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

The difficulties for a photolabile drug in topical formulations: The case of diclofenac
Ioele G, et al.
International Journal of Pharmaceutics, 465(1-2), 284-290 (2014)
N Negreira et al.
Analytical and bioanalytical chemistry, 400(2), 603-611 (2011-02-22)
This work describes an effective, low solvent consumption and affordable sample preparation approach for the determination of eight UV filters in surface and wastewater samples. It involves sorptive extraction of target analytes in a disposable, technical grade silicone disc (5 mm
Morgane Bachelot et al.
The Science of the total environment, 420, 273-279 (2012-02-15)
The accumulation of EHMC, OCT and OD-PABA, three common UV filter compounds, was investigated in marine mussels. Wild Mytilus edulis and Mytilus galloprovincialis were sampled in ten sites along the French Atlantic and Mediterranean coasts from June to November. In
D Kaiser et al.
Environmental pollution (Barking, Essex : 1987), 163, 84-90 (2012-02-14)
Chemical UV filters are used in sun protection and personal care products in order to protect consumers from skin cancer induced by ultraviolet (UV) radiation. The present study aims to evaluate the effects of three common UV filters butyl-methoxydibenzoylmethane (B-MDM)
Martine Avenel-Audran et al.
Archives of dermatology, 146(7), 753-757 (2010-07-21)
Octocrylene is a new emerging photoallergen. We report and discuss 50 cases of photoallergic contact dermatitis from octocrylene use and/or positive photopatch test reactions to this UV filter and draw attention to the unexpected association in adults with a history

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