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Merck
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主要文件

NIST2373

Genomic DNA Standards for HER2 Measurements

NIST®SRM®

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About This Item

分類程式碼代碼:
41116107
NACRES:
NA.24

形狀

liquid

製造商/商標名

NIST®

技術

PCR: suitable
qPCR: suitable

應用

genomic analysis

儲存溫度

2-8°C

一般說明

Genomic DNA Standards are standard reference materials (SRM 2373) containing genomic DNA extracted from five breast cancer cell lines with different amounts of amplification of the HER2 gene. The five components are genomic DNA materials derived from human cell lines SK-BR-3, MDA-MB-231, MDA-MB-361, MDA-MB-453, and BT-474, labeled A, B, C, D, and E, respectively. A unit of SRM 2373 consists of five vials, one of each component, containing approximately 100 μL of DNA solution.

SRM_2373_cert

SRM_2373_SDS

應用

Genomic DNA Standards for HER2 Measurements is intended for use in the assignment of ratios of the human epidermal growth factor receptor 2 gene (HER2, the official gene symbol ERBB2) to unamplified reference genes. It is suitable for use with quantitative polymerase chain reaction (qPCR) and digital polymerase chain reaction (dPCR) assays.

特點和優勢

The use of this material will provide confidence in the assignment of certified ratios to the secondary standard DNA solutions for routine use with qPCR and dPCR assays.

其他說明

  • SRM 2373 is intended for research use. This is a human source material.
  • Expiration details, storage, and usage instructions are provided on the NIST certificate
  • Notes on biomaterial handling, disposal, and transport documented in MSDS

法律資訊

NIST is a registered trademark of National Institute of Standards and Technology
SRM is a registered trademark of National Institute of Standards and Technology

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Hua-Jun He et al.
Biomolecular detection and quantification, 8, 1-8 (2016-06-24)
NIST standard reference material (SRM) 2373 was developed to improve the measurements of the HER2 gene amplification in DNA samples. SRM 2373 consists of genomic DNA extracted from five breast cancer cell lines with different amounts of amplification of the
Hua-Jun He et al.
Clinical chemistry and laboratory medicine, 57(8), 1142-1152 (2019-05-22)
Background The National Institute of Standards and Technology (NIST) Reference Material RM 8366 was developed to improve the quality of gene copy measurements of EGFR (epidermal growth factor receptor) and MET (proto-oncogene, receptor tyrosine kinase), important targets for cancer diagnostics

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