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D7282

Supelco

去甲西泮

analytical standard

别名:

去甲安定

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About This Item

经验公式（希尔记法）:
C15H11ClN2O
CAS号:
1088-11-5
分子量:
270.71
EC號碼:
214-123-4
MDL號碼:
MFCD00063440
分類程式碼代碼:
41116107
PubChem物質ID:
329798847
NACRES:
NA.24

等級

analytical standard

品質等級

100

化驗

≥98% (HPLC)

形狀

powder

藥物控制

USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

技術

HPLC: suitable
gas chromatography (GC): suitable

顏色

white to light tan

溶解度

DMSO: >10 mg/mL

應用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

格式

neat

儲存溫度

room temp

SMILES 字串

Clc1ccc2NC(=O)CN=C(c3ccccc3)c2c1

InChI

1S/C15H11ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)

InChI 密鑰

AKPLHCDWDRPJGD-UHFFFAOYSA-N

基因資訊

rat ... Tspo(24230)

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應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化／生理作用

地西泮的主要代谢物；GABAA 受体苯二氮卓调控位点的配体。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H302

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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分析证书(COA)

Lot/Batch Number
064M4616V
SLBG6159V
043M4607V
050M4627
059K4618

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Pi Cheng et al.
Bioorganic & medicinal chemistry letters, 18(13), 3787-3789 (2008-06-06)
A series of 4-aryl-6-chloro-quinolin-2-ones and 5-aryl-7-chloro-1,4-benzodiazepine were synthesized and assayed for their in vitro anti-hepatitis B virus activities and cytotoxicities for the first time. Some of the tested compounds were active against HBsAg and HBeAg secretion in Hep G2.2.15 cells.
Shanlin Fu et al.
Journal of analytical toxicology, 34(5), 243-251 (2010-06-10)
beta-Glucuronidase is an enzyme often employed to de-conjugate beta-glucuronides during urinary drug testing for benzodiazepines. It is commonly accepted that use of beta-glucuronidase is a preferred method of hydrolysis over acid-catalyzed hydrolysis, which is known to induce benzodiazepine degradation and
David A Fishbain et al.
Pain medicine (Malden, Mass.), 10(3), 565-572 (2008-11-11)
The objectives of this medicolegal case report are the following: 1) to present details of a chronic pain patient (CPP) who was placed on chronic opioid analgesic therapy (COAT), and subsequently overdosed on multiple drugs, some of which were not
Ali Acikgöz et al.
Toxicology and applied pharmacology, 234(2), 179-191 (2008-11-06)
Drug biotransformation is one of the most important parameters of preclinical screening tests for the registration of new drug candidates. Conventional existing tests rely on nonhuman models which deliver an incomplete metabolic profile of drugs due to the lack of
Joris C Verster et al.
Sleep medicine reviews, 17(2), 153-159 (2012-08-14)
The use of benzodiazepine receptor agonists can significantly impair driving performance. The aim of this review was to determine if there is a relation between blood concentrations of these drugs and the degree of driving impairment. A literature search was
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