BP1083

异烟肼

British Pharmacopoeia (BP) Reference Standard

• 别名: 4-吡啶羧酸酰肼, INH, 异烟酸肼, 雷米封
• 经验公式（希尔记法）: C₆H₇N₃O
• CAS号: 54-85-3
• 分子量: 137.14
• Beilstein: 119374
• MDL號碼: MFCD00006426
• 分類程式碼代碼: 41116107

属性

• 等級: pharmaceutical primary standard
• API 家族: isoniazid
• 形狀: powder
• 儲存期限: limited shelf life, expiry date on the label
• 製造商／商標名: BP
• mp: 171-173 °C (lit.)
• 應用: pharmaceutical
• 格式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: NNC(=O)c1ccncc1
• InChI: 1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
• InChI 密鑰: QRXWMOHMRWLFEY-UHFFFAOYSA-N

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Isoniazid BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Isoniazid Oral Solution

生化／生理作用

针对结核菌的抗生素，抑制分枝菌酸的生物合成。由肝脏 N-乙酰转移酶 (NAT) 和 细胞色素 P450 2E1 (CYP2E1) 代谢形成肝毒素。选择性诱导 CYP2E1 的表达。可逆抑制 CYP2C19 和 CYP3A4 的活性，在临床相关浓度下机械性地灭活 CYP1A2、CYP2A6、CYP2C19 和 CYP3A4。

包裝

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302 - H315
• 防範說明: P264 - P280 - P301 + P312 - P302 + P352 - P332 + P313 - P362 + P364
• 危險分類: Acute Tox. 4 Oral - Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3