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About This Item
经验公式（希尔记法）:
C24H14
CAS号:
分子量:
302.37
Beilstein:
2054068
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
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等級
certified reference material
agency
BCR®
製造商／商標名
JRC
技術
HPLC: suitable
gas chromatography (GC): suitable
格式
neat
儲存溫度
2-8°C
SMILES 字串
c1ccc2c(c1)cc3ccc4cccc5c6ccccc6c2c3c45
InChI
1S/C24H14/c1-2-8-18-16(6-1)14-17-13-12-15-7-5-11-20-19-9-3-4-10-21(19)24(18)23(17)22(15)20/h1-14H
InChI 密鑰
JNTHRSHGARDABO-UHFFFAOYSA-N
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分析報告
For more information please see:
BCR096
BCR096
法律資訊
BCR is a registered trademark of European Commission
訊號詞
Danger
危險聲明
危險分類
Carc. 1B - Eye Dam. 1 - Muta. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Fredine T Lauer et al.
Journal of toxicology and environmental health. Part A, 76(1), 16-24 (2012-11-16)
Dibenzo[def,p]chrysene (DBC) is a potent environmental carcinogen in rodents, fish, and human cells examined in culture. There are numerous similarities between the patterns of cytochrome P-450 (P450) activation of DBC and its covalent binding to DNA and proteins with another
Susan Ritger Crowell et al.
Toxicology and applied pharmacology, 257(3), 365-376 (2011-10-18)
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants generated as byproducts of natural and anthropogenic combustion processes. Despite significant public health concern, physiologically based pharmacokinetic (PBPK) modeling efforts for PAHs have so far been limited to naphthalene, plus simpler PK
Kun-Ming Chen et al.
International journal of cancer, 133(6), 1300-1309 (2013-03-14)
We previously reported that dibenzo[a,l]pyrene (DB[a,l]P), the most potent known environmental carcinogen among polycyclic aromatic hydrocarbons (PAH) congeners, is carcinogenic in the oral tissues of mice. We have now developed a new mouse model which employs the oral application of
Yuqin Cai et al.
Biochemistry, 49(46), 9943-9945 (2010-10-23)
The impact of a bulky DNA lesion on the structure and dynamics of a nucleosome core particle (NCP) containing a lesion derived from the unusually potent tumorigen dibenzo[a,l]pyrene that resists nucleotide excision repair (NER) in free DNA was investigated using
Yijin Tang et al.
Biochemistry, 51(48), 9751-9762 (2012-11-06)
The most potent tumorigen identified among the polycyclic aromatic hydrocarbons (PAH) is the nonplanar fjord region dibenzo[a,l]pyrene (DB[a,l]P). It is metabolically activated in vivo through the widely studied diol epoxide (DE) pathway to form covalent adducts with DNA bases, predominantly
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