938963

Potassium tert-butoxide ChemBeads

• 别名: Potassium tert-butylate, Potassium t-butoxide
• 经验公式（希尔记法）: KOC₄H₉
• CAS号: 865-47-4
• 分子量: 112.21
• MDL號碼: MFCD00012162
• 分類程式碼代碼: 12352100

属性

• 描述: Reagent Type-Organic Salt
• 品質等級: 100
• 形狀: solid
• 成份: wt% loading of base, 14-16 wt. %
• 反應適用性: core: potassium
• SMILES 字串: [K+].CC(C)(C)[O-]
• InChI: 1S/C4H9O.K/c1-4(2,3)5;/h1-3H3;/q-1;+1
• InChI 密鑰: LPNYRYFBWFDTMA-UHFFFAOYSA-N

说明

一般說明

Potassium tert-butoxide is a strong alkoxide base, it can deprotonate carbon and other Brφnsted acids. It is a relatively poor nucleophile.

應用

Potassium tert-butoxide has been used as a strong base in the enantioselective synthesis of amines by transfer hydrogenation of N-(tertbutylsulfinyl)imines. It can also be used: To synthesize aliphatic and aromatic amides from corresponding esters and amines. As a base in the intramolecular cyclization of aryl ethers, amines, and amides. As a catalyst to prepare styrene derivatives from aryl halides and alkenes by Mizoroki-Heck reaction.
For general uses, product is also available in powdered form (156671)

特點和優勢

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

其他說明

High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads

Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughput Experimentation

ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand

安全信息

• 象形圖: GHS02,GHS05
• 訊號詞: Danger
• 危險聲明: H228,H252,H314
• 防範說明: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 2 - Skin Corr. 1A
• 安全危害: EUH014
• 儲存類別代碼: 4.2 - Pyrophoric and self-heating hazardous materials
• 水污染物質分類（WGK）: WGK 3