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Merck
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文件

81210

Sigma-Aldrich

聚（乙二醇）

average Mw 1,500

别名:

PEG

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About This Item

线性分子式:
H(OCH2CH2)nOH
CAS号:
25322-68-3
MDL號碼:
MFCD00081839
分類程式碼代碼:
12352104
PubChem物質ID:
24887690
NACRES:
NA.23

形狀

solid

品質等級

200

分子量

average Mw 1,500

mp

45-50 °C

轉變溫度

Tm 45-50 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES 字串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI 密鑰

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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相关类别

一般說明

聚乙二醇 (PEG) 是一种非离子型亲水性聚合物，具有不同的分子量。有助于蛋白质和核酸的纯化和晶体生长。PEG 和葡聚糖形成聚合物双水相系统，用于生物物质的纯化。PEG 还与细胞膜相互作用，从而导致细胞融合。

應用

聚乙二醇已被用于体外培养珠的组织学、组织化学和免疫组织化学评价。已用于细胞融合。

其他說明

分子量范围：1,400-1,600

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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分析证书(COA)

Lot/Batch Number
BCCD3122
BCCB0461
BCBX5256
BCBW2779
BCBT9003

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295906

聚（乙二醇）

Chondrogenesis of human mesenchymal stem cells encapsulated in alginate beads.
Ma HL et al.
Journal of Biomedical Materials Research Part A, 64, 273-273 (2003)
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Angewandte Chemie (International Edition in English), 49, 6288-6308 (2010)
DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents.
Relloso M et al.
Journal of Immunology, 168, 2634-2634 (2002)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
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商品

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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