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Merck

49724

Supelco

丹酚酸 B

analytical standard

别名:

(2 S ,3 S )-4-[(1 E )-3-[(1 R )-1-羧基-2-(3,4-二羟基苯基)乙氧基]-3-氧代-1-丙烯-1-基]-2-(3,4-二羟基苯基)-2,3-二氢-7-羟基-3-苯并呋喃羧酸 3-[(1 R )-1-羧基-2-(3,4-二羟基苯基)乙基] 酯, 丹参酸 B, 丹芬酸 B, 紫草酸 B

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About This Item

经验公式(希尔记法):
C36H30O16
分子量:
718.61
MDL號碼:
分類程式碼代碼:
85151701
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

化驗

≥95.0% (HPLC)

儲存期限

limited shelf life, expiry date on the label

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

food and beverages

格式

neat

儲存溫度

2-8°C

SMILES 字串

OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c3O[C@@H]([C@@H](C(=O)O[C@H](Cc4ccc(O)c(O)c4)C(O)=O)c23)c5ccc(O)c(O)c5

InChI

1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31+,32-/m1/s1

InChI 密鑰

SNKFFCBZYFGCQN-VWUOOIFGSA-N

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一般說明

Salvianolic acid B is a cell protective antioxidant and free radical scavenger being investigated for a variety of conditions from ischemic heart disorders to Alzheimer′s disease.
Salvianolic acid B is one of the main water soluble bioactive components of Salvia miltiorrhiza medicinal plant, the root of which is used in the treatment of dysmenorrhea, coronary heart disease, chronic renal failure, cerebrovascular disease, hypertension, and cytotoxicity against human tumor cell lines.

應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Salvianolic acid B may be used as an analytical reference standard for the quantification of the anayte in the roots of Salvia miltiorrhiza and other related Chinese medicines using chromatography techniques.

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

其他說明

This compound is commonly found in plants of the genus: salvia

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Preparative isolation and purification of salvianolic acid B from the Chinese medicinal plant Salvia miltiorrhiza by high-speed counter-current chromatography
Li B-H, et al.
Journal of Chromatography A, 943(2), 235-239 (2002)
Isolation and purification of salvianolic acid A and salvianolic acid B from Salvia miltiorrhiza by high-speed counter-current chromatography and comparison of their antioxidant activity.
Sun Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(8-9), 733-737 (2009)
Xiaochuan Li et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(2), 234-239 (2006-11-30)
Salviae miltiorrhiza, a traditional Chinese medical herb known as "Danshen," has been widely used in clinics to improve blood circulation, relieve blood stasis, and treat coronary heart disease. Depside salts from S. miltiorrhiza are a novel drug in which magnesium
Hirobumi Yamamoto et al.
Chemical & pharmaceutical bulletin, 50(8), 1086-1090 (2002-08-23)
Cell suspension cultures of Lithospermum erythrorhizon produced a large amount of lithospermic acid B, a caffeic acid tetramer, as well as shikonin derivatives (each ca. 10% of dry wt.) when cultured in shikonin production medium M-9. Various culture factors for
Anja Watzke et al.
Journal of natural products, 69(8), 1231-1233 (2006-08-29)
Salvianolic acid B and lithospermic acid B are the major components of Salvia miltiorrhiza, which is one of the most popular herbal traditional medicines in Asian countries. Salvianolic acid B and lithospermic acid B are reported to have identical structures

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