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Merck
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Key Documents

48305

Millipore

胆盐

suitable for microbiology

别名:

胆汁酸钠盐-脱氧胆酸钠盐混合物, 胆汁酸 钠盐, 胆酸-脱氧胆酸钠盐混合物

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About This Item

MDL號碼:
分類程式碼代碼:
41106212
NACRES:
NA.85

描述

anionic

品質等級

無菌

non-sterile

化驗

40-60% (Cholic Acid ; approximately 50% sodium cholate and approximately 50% sodium deoxycholate, HPLC)

形狀

powder

成份

cholic acid sodium salt, ~50%
deoxycholic acid sodium salt, ~50%

雜質

≤5% water

損耗

≤5% loss on drying (water)

溶解度

H2O: 0.1 g/mL, clear, faintly yellow

應用

microbiology

儲存溫度

10-30°C

一般說明

胆汁盐是一种有机钠盐,包含任何胆汁酸与甘氨酸或牛磺酸的偶联物。胆汁盐由四种不同的胆汁酸组成:胆酸、脱氧胆酸、鹅去氧胆酸和石胆酸。
胆汁盐是在受控条件下由纯化的新鲜胆汁提取出来,可用于细菌培养基,在细胞培养基中它作为一种选择性抑制剂,可以分离和鉴定病原体。例如,麦康凯琼脂/肉汤

應用

在进行的实验中,胆汁盐可以用作选择性试剂之一,以防止受损的大肠杆菌细胞的生长,以鉴定选择性培养基中的特异性试剂,其将抑制受损的大肠杆菌 ML30 细胞的生长。它也可以用于创伤弧菌(贝内克氏菌属)的分离鉴定,它是一种嗜盐菌,可导致几种人类传染病。

生化/生理作用

胆汁盐是表面活性的类固醇化合物,它们的主要生理功能是帮助消化脊椎动物肠道中的亲脂性营养素。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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访问文档库

Eunsil Choi et al.
Frontiers in microbiology, 11, 597515-597515 (2020-11-27)
The BipA (BPI-inducible protein A) protein is ubiquitously conserved in various bacterial species and belongs to the translational GTPase family. Interestingly, the function of Escherichia coli BipA is not essential for cell growth under normal growth conditions. However, cultivation of
Bonggyu Min et al.
Frontiers in bioengineering and biotechnology, 8, 828-828 (2020-08-15)
Stress resistance is an important trait expected of lactic acid bacteria used in food manufacturing. Among the various sources of stress, high temperature is a key factor that interrupts bacterial growth. In this regards, constant efforts are made for the
Bacterial degradation of bile salts.
Philipp B
Applied Microbiology and Biotechnology, 89 (4), 903-915 (2011)
Luis Noriega et al.
International journal of food microbiology, 94(1), 79-86 (2004-06-03)
Six derivatives with increased resistance to ox gall (MIC: > or = 1% w/v) and one derivative resistant to sodium cholate (MIC: 0.8% w/v) were obtained from more sensitive original Bifidobacterium strains. These microorganisms, and two additional cholate resistant derivatives
Leyuan Li et al.
Journal of proteome research, 17(1), 154-163 (2017-11-14)
In vitro culture based approaches are time- and cost-effective solutions for rapidly evaluating the effects of drugs or natural compounds against microbiomes. The nutritional composition of the culture medium is an important determinant for effectively maintaining the gut microbiome in

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