33894

克霉唑

VETRANAL^®, analytical standard

• 别名: 1-[（2-氯苯基）二苯基甲基]-1-H咪唑, 1-（o-氯-α，α-二苯基苄基）咪唑, 1-（o-氯三苯）咪唑
• 经验公式（希尔记法）: C₂₂H₁₇ClN₂
• CAS号: 23593-75-1
• 分子量: 344.84
• EC號碼: 245-764-8
• MDL號碼: MFCD00057220
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329754531
• NACRES: NA.24

属性

• 等級: analytical standard
• 產品線: VETRANAL^®
• 儲存期限: limited shelf life, expiry date on the label
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 抗生素活性譜: fungi
• 應用: agriculture; environmental
• 格式: neat
• 作用方式: protein synthesis | interferes
• SMILES 字串: Clc1ccccc1C(c2ccccc2)(c3ccccc3)n4ccnc4
• InChI: 1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
• InChI 密鑰: VNFPBHJOKIVQEB-UHFFFAOYSA-N

说明

一般說明

Clotrimazole, a non-toxic, systemic, imidazole derivative with broad-spectrum antimycotic activity, is primarily used in the treatment of oropharyngeal candidiasis.

Its mode of action involves the inhibition of ergosterol synthesis, which leads to structural and functional damage of the cell membrane.

應用

Clotrimazole may be used as a reference standard for the determination of the analyte in topical creams and ear drops by reversed-phase high-performance liquid chromatographic (RP-HPLC) method.

Clotrimazole may be used as an analytical reference standard for the determination of the analyte in:

• Milk samples using solid-phase extraction followed by high-performance liquid chromatography (SPE-HPLC).
• Environmental water samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS07,GHS09
• 訊號詞: Warning
• 危險聲明: H302,H315,H319,H410
• 防範說明: P264 - P270 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves