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About This Item
经验公式（希尔记法）:
C22H30O
CAS号:
分子量:
310.47
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
等級
analytical standard
品質等級
產品線
VETRANAL®
儲存期限
limited shelf life, expiry date on the label
技術
HPLC: suitable
gas chromatography (GC): suitable
應用
pharmaceutical (small molecule)
形式
neat
SMILES 字串
CC[C@]12CC(=C)[C@H]3[C@@H](CCC4=CCCC[C@H]34)[C@@H]1CC[C@@]2(O)C#C
InChI
1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1
InChI 密鑰
RPLCPCMSCLEKRS-BPIQYHPVSA-N
基因資訊
human ... PGR(5241)
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一般說明
Desogestrel is a novel progestational steroid developed for utilization in oral contraceptives.
應用
Desogestrel may be used as an analytical reference standard for the determination of the analyte in:
- Contraceptives and river water samples by high performance liquid chromatography/ion-trap mass spectrometry (LC-IT MS).
- Pharmaceutical samples by LC-MS.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
法律資訊
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險聲明
危險分類
Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Evaluation of the sensitivity of miniaturized liquid chromatography-electrospray ionization-mass spectrometry for pharmaceutical analysis.
Kranendijk M, et al.
Journal of Separation Science, 28(14), 1796-1802 (2005)
Gabriele S Merki-Feld et al.
Cephalalgia : an international journal of headache, 33(5), 340-346 (2013-01-09)
Migraine seems to be substantially related to hormonal changes. However, migraine, but also the use of combined oral contraceptives (COC), is associated with an increased risk for vascular events. Therefore progestagen-only contraception is an important alternative to combined preparations. Clinical
High performance liquid chromatography/ion-trap mass spectrometry for separation and simultaneous determination of ethynylestradiol, gestodene, levonorgestrel, cyproterone acetate and desogestrel.
Matejicek D and Kuban V
Analytica Chimica Acta, 588(2), 304-315 (2007)
Tessa Madden et al.
Obstetrics and gynecology, 120(5), 1053-1059 (2012-10-24)
To estimate whether women who receive an immediate postabortion etonogestrel subdermal implant have higher discontinuation rates than women who undergo an interval insertion (insertion not associated with a recent pregnancy). This was a secondary analysis of the Contraceptive CHOICE Project.
Petra M Casey et al.
Contraception, 87(3), 370-374 (2012-09-11)
Bleeding irregularities represent the most common etonogestrel subdermal implant (ESI) removal indication. ESI placements (n=304) from June 2007 to April 2011 were grouped by removal indications. Group characteristics were compared using one-way analysis of variance, Kruskal-Wallis and χ(2) test. Of
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