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等級
ACS reagent
品質等級
形狀
powder
技術
titration: suitable
visual transition interval
3.0-4.6, yellow to blue
mp
273 °C (lit.)
溶解度
ethanol: 0.1%
應用
diagnostic assay manufacturing
hematology
histology
儲存溫度
room temp
SMILES 字串
Oc1c(Br)cc(cc1Br)C2(OS(=O)(=O)c3ccccc23)c4cc(Br)c(O)c(Br)c4
InChI
1S/C19H10Br4O5S/c20-12-5-9(6-13(21)17(12)24)19(10-7-14(22)18(25)15(23)8-10)11-3-1-2-4-16(11)29(26,27)28-19/h1-8,24-25H
InChI 密鑰
UDSAIICHUKSCKT-UHFFFAOYSA-N
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一般說明
溴酚蓝在酸性水溶液中以磺化羟基醌的形式存在。又名四溴酚磺酞。溴酚蓝是一种pH指示剂，并且是一种强蓝色染料。 它带有轻微的负电荷并且与DNA同向迁移，方便用户对分子在凝胶中的移动进程进行监测。不同的凝胶组成具有不同的迁移速率。
應用
溴酚蓝可用作DNA、RNA（琼脂糖）和蛋白（聚丙烯酰胺）凝胶电泳中的示踪染料。它被用于为蛋白质印迹分析制备蛋白质样品。溴酚蓝在琼脂糖凝胶中以与300-500 bp DNA大致相同的速率迁移，在蛋白聚丙烯酰胺凝胶中位于缓冲前沿。 还用作血脑屏障的重要检测染料。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Ibrahim Alkatout et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 28(1), 69-79 (2014-06-21)
The prognosis of pancreatic neuroendocrine tumors is related to size, histology and proliferation rate. However, this stratification needs to be refined further. We conducted a proteome study on insulinomas, a well-defined pancreatic neuroendocrine tumor entity, in order to identify proteins
Dana Westphal et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(39), E4076-E4085 (2014-09-18)
The pivotal step on the mitochondrial pathway to apoptosis is permeabilization of the mitochondrial outer membrane (MOM) by oligomers of the B-cell lymphoma-2 (Bcl-2) family members Bak or Bax. However, how they disrupt MOM integrity is unknown. A longstanding model
Helen Karlberg et al.
The Journal of general virology, 96(Pt 3), 538-546 (2014-12-08)
Pathogenesis of viral haemorrhagic fevers is associated with alteration of vascular barrier function and haemorrhage. To date, the specific mechanism behind this is unknown. Programmed cell death and regulation of apoptosis in response to viral infection is an important factor
Stephanie L Smith-Roe et al.
Oncotarget, 6(2), 732-745 (2014-12-30)
SWI/SNF complexes utilize BRG1 (also known as SMARCA4) or BRM (also known as SMARCA2) as alternative catalytic subunits with ATPase activity to remodel chromatin. These chromatin-remodeling complexes are required for mammalian development and are mutated in ~20% of all human
Siao-Syun Guan et al.
Oncotarget, 5(13), 4868-4880 (2014-06-21)
Colorectal cancer (CRC) is known as a common malignant neoplasm worldwide. The role of EGFR/HER2 in CRC is unclear. Afatinib is an irreversible EGFR/HER2 inhibitor. There were few studies of afatinib on CRC. Here, we investigated the protein levels/expressions of
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