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agency
tested according to Ph. Eur.
品質等級
形狀
solid
分子量
5000-7000
溶解度
aliphatic hydrocarbons: slightly soluble
organic solvents: soluble
應用
pharmaceutical (small molecule)
SMILES 字串
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI 密鑰
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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應用
聚乙二醇用于将西罗莫司固体分散体纳米粒作为亲水性载体进行表征。
生化／生理作用
聚乙二醇 (PEG) 是环氧乙烷和水的缩聚物。增强提取蛋白的复性。 这使得结晶蛋白的表征成为可能。
準備報告
聚乙二醇可溶于许多有机溶剂，易溶于芳香烃。也微溶于脂肪烃。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
Min-Soo Kim et al.
International journal of nanomedicine, 6, 2997-3009 (2011-12-14)
The aim of this study was to improve the physicochemical properties and bioavailability of poorly water-soluble sirolimus via preparation of a solid dispersion of nanoparticles using a supercritical antisolvent (SAS) process. First, excipients for enhancing the stability and solubility of
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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