RMYOMAG-88K
MILLIPLEX® Rat Myokine Magnetic Bead Panel
Inflammation/Immunology Bead-Based Multiplex Assays using the Luminex technology enable the simultaneous analysis of multiple myokine and cytokine biomarkers in rat serum and plasma samples.
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About This Item
分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.47
推荐产品
品質等級
物種活性
rat
製造商／商標名
Milliplex®
assay range
accuracy: 82%
(FGF21)
accuracy: 83%
(IL-15)
accuracy: 85%
(Fractalkine (FKN))
accuracy: 85%
(Irisin)
accuracy: 88%
(IL-6)
accuracy: 91%
(FSTL1)
accuracy: 94%
(LIF)
inter-assay cv: <20%
intra-assay cv: <10%
技術
multiplexing: suitable
檢測方法
fluorometric (Luminex xMAP)
運輸包裝
ambient
一般說明
Skeletal muscle is actively involved in the synthesis and secretion of many proteins collectively termed “myokines.” Muscle contraction during physical activity is an important activator for the release of myokines, which act in an autocrine and/or paracrine manner to regulate skeletal muscle growth. Myokines also act as endocrine hormones which mediate inter-organ crosstalk. Myokine theory provides molecular mechanistic explanations for exercise-induced metabolic changes in liver and adipose tissue as well as for profound changes in immune and neuron systems. Various rat disease models are now serving as exceptional research tools for myokine study.
MILLIPLEX® Rat Myokine Panel is a 12-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum, plasma, and tissue culture samples: Brain-derived Neurotrophic Factor (BDNF), Erythropoeitin (EPO), Fibroblast Growth Factor 21 (FGF21), Follistatin-Like Protein 1 (FSTL-1), Fractalkine (FKN / CX3CL1), IL-6, IL-15, Irisin, Leukemia Inhibitory Factor (LIF), Myostatin (MSTN / GDF8), Osteocrin/Musclin (OSTN), Osteonectin (SPARC). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cytokines/Chemokines
MILLIPLEX® Rat Myokine Panel is a 12-plex kit to be used for the simultaneous quantification of any or all of the following analytes in serum, plasma, and tissue culture samples: Brain-derived Neurotrophic Factor (BDNF), Erythropoeitin (EPO), Fibroblast Growth Factor 21 (FGF21), Follistatin-Like Protein 1 (FSTL-1), Fractalkine (FKN / CX3CL1), IL-6, IL-15, Irisin, Leukemia Inhibitory Factor (LIF), Myostatin (MSTN / GDF8), Osteocrin/Musclin (OSTN), Osteonectin (SPARC). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cytokines/Chemokines
特異性
Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
應用
- Analytes: Brain-Derived Neurotrophic Factor (BDNF), Erythropoietin (EPO), Fibroblast Growth Factor 21 (FGF-21), Follistatin-like Protein 1 (FSTL1), Fractalkine (FKN/CX3CL1), IL-6, IL-15, Irisin, Leukemia Inhibitory Factor (LIF), Growth/Differentiation Factor 8 (GDF8/Myostatin), Osteocrin (OSTN/Musclin), Secreted Protein Acid and Rich in Cysteine (Osteonectin/SPARC)
- Recommended Sample Type: Rat serum, plasma, cell/tissue culture supernatants and lysates
- Recommended Sample Dilution: 25μL per well of 1:2 diluted serum or plasma; cell/tissue culture samples may require dilution in an appropriate control medium.
- Assay Run Time: Overnight (16-18 hours) at 2-8°C
- Research Category: Metabolism, Endocrine
- Research Subcategory: Obesity, Metabolic Disorders Inflammation, Muscle Physiology
特點和優勢
Design your multiplex kit by choosing available analytes within this panel.
包裝
96 well plate
儲存和穩定性
Recommended storage for kit components is 2 - 8°C.
其他說明
Standard curve range: See protocol
法律資訊
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
訊號詞
Danger
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
標靶器官
Respiratory Tract
儲存類別代碼
10 - Combustible liquids
K Gawlinska et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 70(3) (2019-09-21)
A balanced maternal diet is necessary for the proper health and development of offspring. Recent clinical and preclinical studies have strongly indicated that maternal exposure to a high-fat diet (HFD) can have an irreversible impact on the structure and function
相关内容
Myokine analysis with multiplex immunoassays, such as the MILLIPLEX® Human Myokine Panel, allow researchers to simultaneously measure multiple muscle-secreted factors, providing more insights into related diseases.
Learn the benefits of using biomarker detection multiplex immunoassays for laboratory, companion, and agricultural animal research and explore MILLIPLEX® multiplex assays for veterinary medicine and animal health research.
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