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Merck
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Key Documents

MABN501

Sigma-Aldrich

Anti-SUR1 Antibody, clone N289/16

clone N289/16, from mouse

别名:

ATP-binding cassette sub-family C member 8, Sulfonylurea receptor 1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

N289/16, monoclonal

物種活性

human, mouse

物種活性(以同源性預測)

rat (immunogen homology)

技術

immunohistochemistry: suitable
western blot: suitable

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ABCC8(6833)

一般說明

Sulfonylurea receptor 1 (SUR1) is also called ATP-binding cassette sub-family C member 8, and is a member of the ABC transporter superfamily. SUR1 is a putative subunit of the beta-cell ATP-sensitive potassium channel (KATP) and functions as a regulator of ATP-sensitive K+ channels and insulin release.

特異性

This antibody recognizes the C-terminus of SUR1. Representative lot deteted Sur1 in crude brain membrane preparations
in SUR1 wild-type (WT) mouse cell lysate, and demonstrated a loss of signal in SUR1 knockout (KO) mouse cell lysate (Prof. J. Trimmer, University of California, Davis.).

免疫原

Recombinant protein corresponding to the C-terminus of rat SUR1.

應用

Anti-SUR1 Antibody, clone N289/16 is a highly specific mouse monoclonal antibody, that targets SUR & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SUR1 in human thalamus tissue.

品質

Evaluated by Western Blotting in mouse hypothalamus tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SUR1 in 10 µg of mouse hypothalamus tissue lysate.

標靶描述

~ 180 kDa observed

外觀

Format: Purified

分析報告

Control
Mouse hypothalamus tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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