MABF359
Anti-CD11b Antibody (human/mouse), PerCP-Cy5.5, clone M1/70
clone M1/70, 0.2 mg/mL, from rat
别名:
Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD antigen CD11b
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About This Item
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生物源
rat
品質等級
共軛
PerCP-Cy5.5
抗體表格
purified antibody
抗體產品種類
primary antibodies
無性繁殖
M1/70, monoclonal
物種活性
human, mouse
濃度
0.2 mg/mL
技術
flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
同型
IgG2bκ
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... ITGAM(3684)
相关类别
一般說明
The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The M1/70 antibody is widely used as a marker for CD11b expression on mouse macrophages, granulocytes, neutrophils, and NK cells. The antibody is also reported to be cross-reactive for Rhesus macaque CD11b.
免疫原
Immunogen information for this antibody is proprietary information.
應用
Research Category
Inflammation & Immunology
Inflammation & Immunology
This Rat Monoclonal Antibody Anti-CD11b (human/mouse), PerCP-Cy5.5, clone M1/70, Cat. No. MABF359 is validated for use in IP, IHC, FC, IF, FC for the detection of CD11b.
外觀
Size Exclusion Chromatography
Purified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
儲存和穩定性
It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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