MABC42
Anti-Pleiotrophin Antibody, clone 3B10
clone 3B10, from mouse
别名:
pleiotrophin, neurite growth-promoting factor 1, Heparin-binding brain mitogen, heparin binding growth factor 8, Heparin-binding growth-associated molecule, heparin affin regulatory protein, Heparin-binding neurite outgrowth-promoting factor 1, pleiotrop
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About This Item
分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
一般說明
Pleiotrophin (PTN) also called Neurite Growth-promoting Factor 1 (NEGF1) or HARP (Heparin affin regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN plays an important role in development processess and promotion of neurite extension. During embryonic development, pleiotrophin is expressed in the central and peripheral nervous system, lung, kidney, gut and bone. Pleiotrophin is also expressed by several tumor cells and is thought to be involved in tumor angiogenesis. PTN initiates an angiogenic switch in different cancer models and acts as an angiogenic factor. PTN does this through an interaction with endothelial cells to initiate proliferation, migration, and tube formation.
免疫原
Recombinant protein corresponding to chicken Pleiotrophin.
應用
Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected Pleiotrophin in papillary squamous cell carcinoma tissue.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Developmental Neuroscience
Apoptosis - Additional
Developmental Neuroscience
This Anti-Pleiotrophin Antibody, clone 3B10 is validated for use in IH, WB for the detection of Pleiotrophin.
品質
Evaluated by Western Blot in human placenta tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Pleiotrophin in 10 µg of human placenta tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Pleiotrophin in 10 µg of human placenta tissue lysate.
標靶描述
~20 kDa observed
聯結
Replaces: MABD179
外觀
Protein G Purified
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing PBS without 0.05% sodium azide.
儲存和穩定性
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
分析報告
Control
Human placenta tissue lysate
Human placenta tissue lysate
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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