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Merck
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Key Documents

MAB4337

Sigma-Aldrich

抗-UTF-1抗体,克隆5G10.2

clone 5G10.2, Chemicon®, from mouse

别名:

Anti-AI505934

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

5G10.2, monoclonal

物種活性

mouse, human

製造商/商標名

Chemicon®

技術

ELISA: suitable
immunocytochemistry: suitable
western blot: suitable

輸入

sample type induced pluripotent stem cell(s)
sample type: mouse embryonic stem cell(s)
sample type: human embryonic stem cell(s)

同型

IgG1κ

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... UTF1(8433)

一般說明

UTF1是一种转录因子,最初是由于其在胚胎干(ES)细胞、胚胎性癌(EC)细胞和种系组织中的表达而被鉴定的。 在成人组织中未发现表达。 当时认为UTF1可能在胚胎发生的早期分子事件中起重要作用。 随后的研究表明,UTF1是Oct-4/Sox-2复合物的靶标,Oct-4/Sox-2复合物是干细胞多能性的关键决定因素

免疫原

重组GST融合蛋白,人UTF-1

應用

抗UTF-1抗体,克隆5G10.2检测UTF-1水平,&已发布&验证可用于ELISA、WB&IC。

外觀

形式:纯化

其他說明

浓度:关于批次特定浓度请参见检验报告。

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Xiao-Ling Wu et al.
Carcinogenesis, 34(7), 1660-1668 (2013-03-29)
Undifferentiated embryonic cell transcription factor-1 (UTF1) is an important transcription factor during development, which plays critical roles in cell fate determination. However, its expression and function in somatic tissues remain unclear. Here, we investigated the expression pattern of the UTF1
M Nishimoto et al.
Molecular and cellular biology, 19(8), 5453-5465 (1999-07-20)
UTF1 is a transcriptional coactivator which has recently been isolated and found to be expressed mainly in pluripotent embryonic stem (ES) cells (A. Okuda, A. Fukushima, M. Nishimoto, et al., EMBO J. 17:2019-2032, 1998). To gain insight into the regulatory
Functional characterization of single-nucleotide polymorphisms in the human undifferentiated embryonic-cell transcription factor 1 gene.
Rajkumar P Thummer,Loes J Drenth-Diephuis,Karen E Carney,Bart J L Eggen
Dna and Cell Biology null
Characterization of human UTF1, a chromatin-associated protein with repressor activity expressed in pluripotent cells.
Susanne M Kooistra,Rajkumar P Thummer,Bart J L Eggen
Stem Cell Research null
Presumed pluripotency markers UTF-1 and REX-1 are expressed in human adult testes and germ cell neoplasms.
Kristensen, DM; Nielsen, JE; Skakkebaek, NE; Graem, N; Jacobsen, GK; Rajpert-De Meyts, E; Leffers, H
Human Reproduction null

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