推荐产品
生物源
mouse
品質等級
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
6C1, monoclonal
物種活性
mouse, sheep, rat, human, chicken, Xenopus
製造商／商標名
Chemicon®
技術
ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
同型
IgM
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... DAG1(1605)
特異性
Cranin (dystroglycan), extracellular site, near the C-terminus of the alpha-subunit. The expression and localization of cranin varies considerably according to the cells physiologic state and differentiaion state. MAB371 recognizes the same peptide region as MAB373 but a different epitope.
免疫原
Epitope: aa572-604 of human sequence
Synthetic peptide corresponding to a.a. 572-604 of human cranin.
應用
Immunohistochemistry on tissue fixed briefly with 0.5% glutaraldehyde, 2% PLP fixation, methanol or acetone. Prolonged fixation must be avoided. Traditional formalin is not recommended. Suggested working dilution 1:1-1:50.
Immunocytochemistry on neuron, astrocyte, smooth muscle, fibroblast and epithelial cell lines.
ELISA
Not suggested for use in Western blot.
Optimal working dilutions must be determined by end user.
Immunocytochemistry on neuron, astrocyte, smooth muscle, fibroblast and epithelial cell lines.
ELISA
Not suggested for use in Western blot.
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
ECM Proteins
Cytoskeleton
ECM Proteins
This Anti-Cranin Antibody, aa572-604 of human sequence, clone 6C1 is validated for use in ELISA, IC, IH for the detection of Cranin.
外觀
Ascites Liquid.
儲存和穩定性
Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Purificaiton of Cranin, a laminin binding membrane protein
Smalheiser, NR and Kim, E.
The Journal of Biological Chemistry, 270, 15425-15433 (1995)
B J Collins et al.
Endocrinology, 142(7), 3152-3162 (2001-06-21)
Dystroglycan is a high affinity laminin-binding glycoprotein originally described as a member of the dystrophin-associated glycoprotein complex in muscle. We have demonstrated the presence of dystroglycan in the thyroid using immunocytochemistry, immunoblots, ligand binding assays, and relative quantitative RT-PCR. In
X Li et al.
The Journal of cell biology, 153(4), 811-822 (2001-05-16)
Fibroblast growth factors and receptors are intimately connected to the extracellular matrix by their affinity to heparan sulfate proteoglycans. They mediate multiple processes during embryonic development and adult life. In this study, embryonic stem cell-derived embryoid bodies were used to
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