推荐产品
生物源
mouse
品質等級
共軛
ALEXA FLUOR™ 488
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
A2B5-105 (7), monoclonal
物種活性
mouse, chicken, human, rat
製造商／商標名
Chemicon®
技術
immunocytochemistry: suitable
immunohistochemistry: suitable
同型
IgM
運輸包裝
wet ice
目標翻譯後修改
unmodified
特異性
The antibody recognizes an epitope common to silaogangliosides and sulfatides from the plasma membranes of neurons, and neuroendocrine and glial cells. Anti-A2B5 has been used to specifically stain:
· Neurofibrillary tangles in the post-mortem brain tissue of patients with a confirmed diagnosis of Alzheimer′s disease (Majocha et al., 1989)
· Neurons of chicken retina, brain, spinal cord, and dorsal root ganglia (Schnitzer & Schachner, 1982; Eisenbarth et al., 1979.
· Rat striatal nerve terminals [synaptosomes (Wolf & Kapatos, 1989].
· Neuroblastoma cells in man (Oppedal et al., 1989; Coakham et al., 1985).
· Rat insulinoma cells and pancreatic islets cells (Shimizu et al., 1983; Bartholomeusz et al., 1989).
· Human and rat thymic epithelial cells (Haynes, et al., 1988).
· Cells involved in gliogenesis (Bottenstein et al., 1988; Suzumura & slerberg, 1989).
· Oligodendrocytes and astrocytes, type II (Dubois-Dalcq et al., 1990).
· Neurofibrillary tangles in the post-mortem brain tissue of patients with a confirmed diagnosis of Alzheimer′s disease (Majocha et al., 1989)
· Neurons of chicken retina, brain, spinal cord, and dorsal root ganglia (Schnitzer & Schachner, 1982; Eisenbarth et al., 1979.
· Rat striatal nerve terminals [synaptosomes (Wolf & Kapatos, 1989].
· Neuroblastoma cells in man (Oppedal et al., 1989; Coakham et al., 1985).
· Rat insulinoma cells and pancreatic islets cells (Shimizu et al., 1983; Bartholomeusz et al., 1989).
· Human and rat thymic epithelial cells (Haynes, et al., 1988).
· Cells involved in gliogenesis (Bottenstein et al., 1988; Suzumura & slerberg, 1989).
· Oligodendrocytes and astrocytes, type II (Dubois-Dalcq et al., 1990).
免疫原
Embryonic chicken retinal cells
應用
Anti-Neuron Cell Surface Antigen Antibody, clone A2B5-105 (7), Alexa Fluor 488 detects level of Neuron Cell Surface Antigen & has been published & validated for use in IC, IH.
Immunocytochemistry
Immunohistochemistry: 1:30
Optimal working dilutions must be determined by end user.
Immunohistochemistry: 1:30
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
外觀
Purified immunoglobulin conjugated to Alexa Fluor™ 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide.
儲存和穩定性
Maintain at 2-8°C in undiluted aliquots in the dark for up to 6 months after date of receipt.
其他說明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律資訊
ALEXA FLUOR is a trademark of Life Technologies
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Alexa Fluor™ is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
The effect of TGF-beta2 on elastin, type VI collagen, and components of the proteolytic degradation system in human optic nerve astrocytes.
Neumann, Carolin, et al.
Investigative Ophthalmology & Visual Science, 49, 1464-1472 (2008)
Pancreatic islet A2B5- and 3G5-reactive gangliosides are markers of differentiation in rat insulinoma cells.
Bartholomeusz, R K, et al.
Endocrinology, 124, 2680-2685 (1989)
Flow cytometric analysis of rat striatal nerve terminals
Wolf, M E and Kapatos, G
The Journal of Neuroscience, 9, 94-105 (1989)
B F Haynes et al.
The Journal of clinical investigation, 71(1), 9-14 (1983-01-01)
Using a monoclonal antibody (A2B5), which binds to GQ ganglioside, and tetanus toxin, which binds to GD and GT gangliosides, distinct regions of human and rodent thymic epithelial cells have been identified. The lymphoid elements of the thymus do not
Bone marrow examination in neuroblastoma patients: a morphologic, immunocytochemical, and immunohistochemical study
Oppedal, B R, et al
Human Pathology, 20, 800-805 (1989)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门