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Merck
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主要文件

MAB2000

Sigma-Aldrich

Anti-Integrin β1 Antibody, clone HB1.1

clone HB1.1, Chemicon®, from mouse

别名:

CD29

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
無性繁殖:
HB1.1, monoclonal
application:
FACS
IHC
IP
WB
物種活性:
human, pig
技術:
flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
citations:
21

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

HB1.1, monoclonal

物種活性

human, pig

製造商/商標名

Chemicon®

技術

flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG1κ

適合性

not suitable for activity/function inhibition

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ITGB1(3688)

特異性

Reacts with beta-1 subunit of VLA integrins

應用

Anti-Integrin β1 Antibody, clone HB1.1 detects level of Integrin β1 & has been published & validated for use in FC, IP, WB, IH.
Immunoprecipitation of VLA integrins from lysate of 10E6 cell equivalent requires 2 μg of MAB2000.

Flow cytometry: 10 μg/mL

Western blot

Immunohistochemistry in frozen tissue samples: 5 μg/mL

Induction of cell aggregation: 10 μg/mL. MAB2000 is a potent stimulator of cell aggregation tested in U937, Jurkat and human peripheral blood lymphocytes.

MAB2000 does not affect VLA integrin-mediated cell adhesion to matrix proteins.

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

聯結

Replaces: 04-1109

外觀

Format: Purified
Purified immunoglobulin from Protein A chromatography. Liquid in 0.02M PB pH 7.6, 0.25M NaCl with 0.1% sodium azide.

儲存和穩定性

Maintain at 2-8°C for up to 6 months after date of receipt.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility.
Seales, EC; Jurado, GA; Brunson, BA; Wakefield, JK; Frost, AR; Bellis, SL
Cancer Research null
PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells.
Toyoshima, F; Matsumura, S; Morimoto, H; Mitsushima, M; Nishida, E
Developmental Cell null
Hyposialylation of integrins stimulates the activity of myeloid fibronectin receptors.
Semel, AC; Seales, EC; Singhal, A; Eklund, EA; Colley, KJ; Bellis, SL
The Journal of Biological Chemistry null
Pig chondrocyte xenoimplants for human chondral defect repair: an in vitro model.
Fuentes-Boquete, Isaac, et al.
Wound Repair and Regeneration, 12, 444-452 (2004)
Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Galphas protein.
Francis J Alenghat,Jessica D Tytell,Charles K Thodeti,Alexandrine Derrien,Donald E Ingber
Journal of Cellular Biochemistry null

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