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Merck
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Key Documents

MAB19294

Sigma-Aldrich

Anti-Integrin β1 Antibody, active β1 integrins, clone TASC/9D11

clone TASC/9D11, Chemicon®, from mouse

别名:

CD29

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

TASC/9D11, monoclonal

物種活性

chicken

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunoprecipitation (IP): suitable

同型

IgG1

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ITGB1(3688)

特異性

Reactive with the extracellular domain of chicken integrin beta 1

免疫原

E10 chick brain glial cells
Epitope: active beta1 integrins

應用

Detect the Integrin β1 protein using this Anti-Integrin β1, active β1 integrins, clone TASC/9D11 validated for use in IP & ICC.
Western blot: Not effective

Immunocytochemistry

Immunoprecipitation

Biological activity: Functionally inhibits attachment to vitronectin. Activates attachment to other substrates.



Optimal working dilutions must be determined by end user.

外觀

Format: Purified
Purified immunoglobulin. Liquid in 0.02M PB +0.25 M NaCl, pH=7.6 with 0.1% Sodium Azide.

儲存和穩定性

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Vitronectin and thrombospondin promote retinal neurite outgrowth: developmental regulation and role of integrins.
Neugebauer, K M, et al.
Neuron, 6, 345-358 (1991)
L R Strachan et al.
Experimental cell research, 314(3), 441-452 (2007-11-27)
Cell migration is essential for proper development of numerous structures derived from embryonic neural crest cells (NCCs). Although recent work has shown that receptor recycling plays an important role in NCC motility on laminin, the molecular mechanisms regulating NCC motility
Combined integrin activation and intracellular cAMP cause Rho GTPase dependent growth cone collapse on laminin-1.
M L Lemons, M L Condic
Experimental neurology null
Cell-surface regulation of beta 1-integrin activity on developing retinal neurons.
Neugebauer, K M and Reichardt, L F
Nature, 350, 68-71 (1991)
Liliana Osório et al.
The International journal of developmental biology, 53(4), 641-648 (2009-02-28)
In the prospective lumbo-sacral region of the chick embryo, neurulation is achieved by cavitation of the medullary cord, a process called secondary neurulation. Neural crest cells (NCC) are generated in this region and they give rise to the same types

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