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Merck
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Key Documents

MAB1567A4

Sigma-Aldrich

Anti-MAG Antibody, clone 513, Alexa Fluor 488 Conjugate

clone 513, from mouse, ALEXA FLUOR 488

别名:

Myelin-associated glycoprotein, Siglec-4a

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

共軛

ALEXA FLUOR 488

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

513, monoclonal

物種活性

rat, mouse

物種活性(以同源性預測)

chicken (based on 100% sequence homology), human (based on 100% sequence homology), frog (based on 100% sequence homology), bovine (based on 100% sequence homology)

技術

immunocytochemistry: suitable
immunohistochemistry: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... MAG(4099)

一般說明

Myelin-associated glycoprotein (MAG), a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS.

免疫原

L2 epitope carrying glycoprotein extract of 1-2 day old chicken brain

應用

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected MAG in rat E18 primary cortex cells.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
This Anti-MAG Antibody, clone 513, Alexa Fluor 488 Conjugate is validated for use in IC, IH for the detection of MAG.

品質

Evaluated by Immunohistochemistry in adult mouse brain tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected MAG in adult mouse brain tissue.

標靶描述

69 kDa calculated

外觀

Protein A purified
Purified mouse monoclonal IgG1 conjugated to Alexa Fluor 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

儲存和穩定性

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析報告

Control
Adult mouse brain tissue

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Allison Y Louie et al.
Journal of neuroinflammation, 20(1), 190-190 (2023-08-19)
Recent data suggest that myelin may be altered by physiological events occurring outside of the central nervous system, which may cause changes to cognition and behavior. Similarly, peripheral infection by non-neurotropic viruses is also known to evoke changes to cognition

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