HMMP2MAG-55K
MILLIPLEX® 人MMP磁珠板2-免疫学多重检测
Matrix Metalloproteinase Bead-Based Multiplex Assays using the Luminex technology enable the simultaneous analysis of multiple MMPs biomarkers in human serum, plasma and cell culture samples.
别名:
Human matrix metalloproteinase multiplex kit, Luminex® Human MMP immunoassay, Millipore human MMP panel
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About This Item
分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.84
品質等級
物種活性
human
製造商/商標名
Milliplex®
assay range
accuracy: 72-98%
standard curve range: 14-10,000 pg/mL
(MMP-9)
standard curve range: 27-20,000 pg/mL
(MMP-1)
standard curve range: 27-20,000 pg/mL
(MMP-10)
standard curve range: 548-400,000 pg/mL
(MMP-7)
standard curve range: 68-50,000 pg/mL
(MMP-2)
技術
multiplexing: suitable
檢測方法
fluorometric (Luminex xMAP)
運輸包裝
wet ice
一般說明
基质金属蛋白酶(MMPs)是一种锌蛋白酶家族,负责细胞外基质(ECM)的分解,在正常的生理过程中起着关键作用,例如胚胎发育和组织形态发生、组织和骨骼重塑、伤口愈合和血管生成。这些过程依赖于MMPs在细胞表面受体的裂解,凋亡配体的释放,细胞增殖和分化以及趋化因子活性调节中的作用。在结构上相似,MMP作为无活性原酶合成并分泌,需要蛋白水解裂解才能激活。该过程可以由丝氨酸蛋白酶或其他MMP介导。MMP表达的增加是对多种刺激(包括粘连分子,生长因子,细胞因子和激素)的响应而发生的。MMP活性的调节主要由TIMP(金属蛋白酶的组织抑制剂)控制。因此,MMP/TIMP平衡的破坏可导致关节炎、心血管疾病和肿瘤生长以及转移。
MMP/TIMP研究对于更深入地了解慢性炎症、心血管疾病和癌症等疾病状态发挥重要作用。
MILLIPLEX® 人MMP珠面板2(MMP-1,-2,-7,-9,-10)将使您能够探索多个治疗领域中MMP表达的调节和功能。
Luminex® xMAP®平台使用磁珠免疫分析格式,以实现理想的速度和灵敏度,同时定量多种分析物,从而显著提高生产力,同时节省宝贵的样本量。
面板类型:细胞因子/趋化因子
MMP/TIMP研究对于更深入地了解慢性炎症、心血管疾病和癌症等疾病状态发挥重要作用。
MILLIPLEX® 人MMP珠面板2(MMP-1,-2,-7,-9,-10)将使您能够探索多个治疗领域中MMP表达的调节和功能。
Luminex® xMAP®平台使用磁珠免疫分析格式,以实现理想的速度和灵敏度,同时定量多种分析物,从而显著提高生产力,同时节省宝贵的样本量。
面板类型:细胞因子/趋化因子
特異性
交叉反应性
在该面板的分析物之间未观察到显著的交叉反应性。
在该面板的分析物之间未观察到显著的交叉反应性。
應用
- 分析物:MMP-1,MMP-2,MMP-7,MMP-9,MMP-10
- 推荐的样品类型:人血清,血浆,组织/细胞裂解液和培养上清液样品
- 推荐的样品稀释度:1:20
- 分析运行时间:一天
- 研究类别:炎症 & 免疫学
特點和優勢
通过在此面板中选择可用的分析物来设计多重试剂盒。
儲存和穩定性
试剂盒组分建议的存储温度为2-8°C。
其他說明
灵敏度:单个分析物的灵敏度见方案。
法律資訊
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
訊號詞
Danger
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
標靶器官
Respiratory Tract
儲存類別代碼
10 - Combustible liquids
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