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用途
-1 kit -96 wells
品質等級
物種活性
human
製造商／商標名
Milliplex®
參數
-25 μL sample volume (per well)
檢測方法
fluorometric (Luminex® xMAP®)
運輸包裝
wet ice
儲存溫度
2-8°C
一般說明
Interferons (IFNs) are widely expressed cytokines that have potent antiviral and antiproliferative effects. These cytokines are the first line of defense against viral infections and have important roles in immunosurveillance for malignant cells. IFNs are classified as type I, II and III IFNs, based upon the target receptors to which they bind. In humans, type I IFNs belong to a multigene family consisting of multiple IFNα subtypes but only one IFNβ, IFNε, IFNκ, and IFNω. There is only one type II IFN: IFNγ. The type III IFNs include IFNλ1, λ2 and λ3, which are also known as interleukin-29 (IL-29), IL 28A and IL-28B, respectively. Functionally, the type I and type III IFNs are induced during a viral infection and involved in host defense against viruses. IFNγ (type II) is primarily involved in the allergic response, in host defense against intracellular pathogens, and in control of tumor growth. Studies of IFNs have broadened the mechanistic understanding of cell signaling, gene transcription, and innate and acquired immunity.
Research category: Inflammation & Immunology
Research sub-category:
Research category: Inflammation & Immunology
Research sub-category:
- Inflammation & Autoimmune Mechanisms
- Inflammation
特異性
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
應用
The MILLIPLEX® Human Interferon Magnetic Bead Panel is a 9-plex kit to be used for the simultaneous quantification of the following analytes in serum or plasma samples and tissue/cell lysate and culture supernatant samples: IFNα-2, IFNβ, IFNε, IFNɣ, IFNɣ Receptor 1, IFNλ1, IFNλ2, IFNλ3, IFNω.
特點和優勢
Design your multiplex kit by choosing available analytes within this panel.
法律資訊
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
標靶器官
Respiratory Tract
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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