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Merck
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Key Documents

CH2900018

SAFC

Calcium Levofolinate Hydrate / Levoleucovorin Calcium Pentahydrate

Ph. Eur.

制药生产

别名:

L-Calcium Folinate, L-Leucovorin Calcium, Levofolinate Calcium Hydrate, Levoleucovorin Calcium

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About This Item

生物源

synthetic

品質等級

等級

GMO free
GMP
Halal
Kosher

agency

Ph. Eur.
USP

形狀

powder

應用

liquid formulation
pharmaceutical
solid formulation

儲存溫度

2-8°C

一般說明

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Calcium Levofolinate Hydrate has three main clinical applications:
1) First line treatment for colorectal cancer: In combination with the anticancer drug 5-fluorouracil (5-FU), Irinotecan, Cisplatin or Oxaliplatin, and its derivatives. Calcium Folinate is a modulator of 5-FU and enhances its efficacy in cancer chemotherapy.
2) Treatment of certain neoplastic diseases, severe psoriasis, and adult rheumatoid arthritis as a rescue therapy to reduce the toxic side effects of intermediate or high doses of methotrexate.
3) Treatment of anemia caused by folate deficiency.

包裝

Customized packaging possible

法律資訊

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

相關產品

产品编号
说明
价格

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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