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Key Documents

CBL468

Sigma-Aldrich

抗-PECAM-1抗体,人PECAM-1结构域3-6,克隆HC1/6

clone HC1/6, Chemicon®, from mouse

别名:

CD31

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

無性繁殖

HC1/6, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... PECAM1(5175)

特異性

与一个130-140 kDa的跨膜糖蛋白反应,该糖蛋白在血管间室的细胞中广泛表达。 CD31在扁桃体、肺和肾脏的血小板、培养内皮细胞、单核细胞、正常组织巨噬细胞以及结节病和麻风病等疾病的皮肤活检组织中表达。
FUSION PARTNER:P3-x63Ag8.653骨髓瘤细胞系

免疫原

表位:人PECAM-1的结构域3-6

應用

CD31在白细胞向炎症部位迁移和血管生成过程中的作用研究

该抗体会在冷冻组织切片上染色

适用于免疫沉淀研究

适用于标记FITC或R-PE时的间接或直接流式细胞术

适用于蛋白酶预处理后的福尔马林固定石蜡包埋切片。

最佳工作稀释度必须由最终用户进行确定。
抗-PECAM-1抗体,人PECAM-1结构域3-6,克隆HC1/6是抗PECAM-1抗体,适用于FC、IH、IH(P) & IP。

外觀

形式:纯化

分析報告

对照
活化的小胶质细胞

其他說明

浓度:请参考批次特异性浓缩物的检验报告。

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Fumiko Obata et al.
Toxins, 14(2) (2022-02-25)
Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown. We determined Stx receptor Gb3 in murine and human kidneys and confirmed
Yu-Ting Huang et al.
Cellular signalling, 20(8), 1521-1527 (2008-05-27)
Sphingosine 1-phosphate (S1P) is a multifunctional phospholipid which acts through a specific family of G protein-coupled receptors. Platelet/endothelial cell adhesion molecule-1 (PECAM-1) form trans-homophilic binding at lateral cell border. Upon stimulation, its cytoplasmic tyrosine residues could be phosphorylated and interact
Guiting Lin et al.
Stem cells and development, 17(6), 1053-1063 (2008-07-04)
Adipose tissue-derived stem cells (ADSC) are routinely isolated from the stromal vascular fraction (SVF) of homogenized adipose tissue. Freshly isolated ADSC display surface markers that differ from those of cultured ADSC, but both cell preparations are capable of multipotential differentiation.
Gina Lisignoli et al.
Journal of cellular physiology, 220(2), 401-409 (2009-04-15)
Bone marrow stromal cells (MSCs) and osteoblasts are the two main non-haematopoietic cellular components of human bone tissue. To identify novel osteoblast-related molecules, we performed a gene expression profiling analysis comparing MSCs and osteoblasts isolated from the same donors. Genes
Characterisation of a novel myeloid antigen regulated during differentiation of monocytic cells
Carbanas, C. et al.
European Journal of Immunology, 19, 1373-1378 (1989)

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