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Key Documents

CBL2117

Sigma-Aldrich

Anti-Interleukin-6 Antibody, clone B-E8

clone B-E8, Chemicon®, from mouse

别名:

IL-6, B-cell stimulatory factor 2, Interferon beta-2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

100
300

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

B-E8, monoclonal

物種活性

human

應無反應活性

mouse

製造商/商標名

Chemicon®

技術

ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable
neutralization: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

基因資訊

human ... IL6(3569)

特異性

Recognizes natural and recombinant forms of human Interleukin-6 with an affinity of 0.5 nM. Inhibits IL-6 binding to its receptors and blocks Interleukin-6 induced proliferation on B9 cells.

免疫原

Recombinant human IL-6.

應用

Blocks Interleukin-6 induced proliferation on B9 cells: 20pg of antibody neutralizes the activity of 1U of IL-6. It is recommended that the sodium azide is removed from the antibody prior to use in this application.

Immunohistochemistry on frozen sections

Optimal working dilutions must be determined by the end user.
Detect Interleukin-6 using this Anti-Interleukin-6 Antibody, clone B-E8 validated for use in ELISA, FC, IH, NEUT.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

聯結

Replaces: 04-1095

外觀

Format: Purified
The monoclonal is purified from tissue culture supernatant by ion exchange chromatography and is presented as a liquid in phosphate buffered saline, pH 7.2.

儲存和穩定性

Store at 2-8°C for up to 12 months from date of receipt. For long term storage aliquot antibody into small volumes and store at -20°C. Avoid repeated freeze-thaw cycles.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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Berberine inhibits inflammatory response and ameliorates insulin resistance in hepatocytes.
Tianjiong Lou,Zhongai Zhang,Zhilei Xi,Kang Liu,Lin Li,Baolin Liu,Fang Huang
Inflammation null
Elevated levels of IL-18 in plasma and skeletal muscle in chronic obstructive pulmonary disease.
A M W Petersen,M Penkowa,M Iversen,L Frydelund-Larsen,J L Andersen,J Mortensen,P Lange,B K Pedersen
Lung null
Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise.
Penkowa, M; Keller, C; Keller, P; Jauffred, S; Pedersen, BK
Faseb Journal null
Fang Huang et al.
Biochimie, 94(5), 1143-1150 (2012-02-09)
Puerarin is an isoflavonoid isolated from the root of the plant Pueraria lobata and has been used as a prescribed drug in China for the treatment of cardiovascular diseases in the clinical practice. Puerarin possesses potential therapeutic activities for metabolic
Microglia derived IL-6 suppresses neurosphere generation from adult human retinal cell suspensions.
Balini Balasubramaniam,Debra A Carter,Eric J Mayer,Andrew D Dick
Experimental Eye Research null

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